bronchitis/edema

SEQUENCE LISTING The instant application contains a Sequence Listing, which is entitled QUARK0005US_SeqListing.txt, created on Aug. 30, 2013 and 2280 kb in size, and is hereby incorporated by reference in its entirety. Throughout this application various patents and publications are cited. The

SEQUENCE LISTING The instant application contains a Sequence Listing, which is entitled 115340_22802_sequence listing 28OCT15.txt, submitted on Oct. 28, 2015 and 2,279.79 kb in size and is hereby incorporated by reference in its entirety. Throughout this application various patents and publications

This application is related to, not a continuing case to U.S. Pat. Nos. 6,172,060, 6,197,778, 6,177,428, 6,172,068, 6,221,881, 6,232,321, 6,197,782, 6,133,272, and 6,211,179. FIELD OF THE INVENTION The present invention describes novel nitrosated and/or nitrosylated phosphodiesterase inhibitors, and

FIELD OF THE INVENTION The present invention describes novel nitrosated and/or nitrosylated phosphodiesterase inhibitors, and novel compositions comprising at least one nitrosated and/or nitrosylated phosphodiesterase inhibitor, and, optionally, at least one compound that donates, transfers or

FIELD OF THE INVENTION The present invention describes novel nitrosated and/or nitrosylated phosphodiesterase inhibitors, and novel compositions comprising at least one nitrosated and/or nitrosylated phosphodiesterase inhibitor, and, optionally, at least one compound that donates, transfers or

BACKGROUND OF THE INVENTION Throughout this application various publications are referenced by numbers. The full citations are listed at the end of the specification immediately preceeding the claims. The proteinase-antiproteinase concept of emphysema has served to focus research on the role of

BACKGROUND Inflammation often is a bodily response to infection or injury in which cells involved in detoxification and repair are mobilized to the compromised site by inflammatory mediators. The infection or injury can result from any of a variety of causes including acute or chronic disease,

CROSS REFERENCE TO RELATED APPLICATION The present invention is based on, and claims priority from 60/008,390, filed Dec. 8, 1995. BACKGROUND OF THE INVENTION This application is directed to inhibitors of nitric oxide synthase, and in particular substituted azacycle derivatives. Nitric Oxide in

BACKGROUND OF THE INVENTION This application is directed to inhibitors of Nitric oxide synthase, and in particular cyclic amidines. Nitric Oxide in Biology. The emergence of nitric oxide (NO), a reactive, inorganic radical gas as a molecule contributing to important physiological and pathological