iatrogenic disease/세로토닌

Serotonin syndrome is an iatrogenic disorder induced by pharmacologic treatment with serotonergic agents that increases serotonin activity. In addition, there is a wide variety of clinical disorders associated with serotonin excess. The frequent concurrent use of serotonergic and neuroleptic drugs

Older people are often exposed to polypharmacy in a multimorbidity context. Inappropriate polypharmacy is often harmful, increasing the risk of inappropriate prescriptions and therefore adverse drug events (ADEs). Five to 20% of all hospital admissions are related to ADE in older people, among which

BACKGROUND Serotonin syndrome is an iatrogenic disorder that results from serotonergic overactivity. Severe myoclonus and increased restlessness are hallmarks of the disorder. METHODS We report a case of serotonin syndrome related to poor drug elimination. RESULTS A 74-year-old white female with

Prescribe in the elderly has specifcities, with age-related pharmacologica modifications, polypharmacy, and risk of drug toxicity. At time of the prescription renewal, each drug must be re-evaluated. The objective of this study was to identify the nature and reasons of drugs modifications during a

Drug interactions can cause iatrogenic disease. If concurrent medications are taken, the potential exists for a drug interaction to occur. Renewed interest in the topic interactions has been generated by the fatal interactions involving non-sedating histamine H-1 antagonists and the recent