migraine disorders/구역질

BACKGROUND Migraine is a condition that affects approximately 28 million people in the United States, with females more frequently affected than males (Silberstein, Neurology, 2000 55:754-63). Migraine headache is associated with a painful vasodilation of cranial vessels that typically manifests in

BACKGROUND Migraine is a condition that affects approximately 28 million people in the United States, with females more frequently affected than males (Silberstein, Neurology, 2000 55:754-63). Migraine headache is associated with a painful vasodilation of cranial vessels that typically manifests in

FIELD OF THE INVENTION The present invention relates to the use of S-alkylisothiouronium derivatives, including, but not limited to, S-ethylisothiouronium diethylphosphate, for the prevention or treatment of headache, including but not limited to migraine, and for the prevention or treatment of

FIELD OF THE INVENTION The present invention relates to the use of S-alkylisothiouronium derivatives, including, but not limited to, S-ethylisothiouronium diethylphosphate, for the prevention or treatment of headache, including but not limited to migraine, and for the prevention or treatment of

FIELD OF THE INVENTION The present invention concerns a coated vaginal device for delivery of anti-migraine and/or anti-nausea drugs and a method for treatment of migraine and nausea. The vaginal device, such as a vaginal tampon, vaginal tampon-like foam or another vaginal device is completely or

FIELD OF THE INVENTION The present invention relates generally to compositions and methods used to alleviate the symptoms and pain associated with an acute migraine attack. BACKGROUND OF THE INVENTION An estimated 24 to 26 million Americans--about 18% of women and 6% of men--suffer from migraine

FIELD OF THE INVENTION The present invention relates generally to compositions and methods used to alleviate the symptoms and pain associated with acute migraine attack. More particularly, the present invention relates to the use of a nonprescription combination of acetaminophen, aspirin and

BACKGROUND OF THE INVENTION In the United States, more than 37 million people suffer from migraines. Migraines are associated with decreased productivity and have a deleterious effect on quality of life. It is estimated that the total cost of lost productive time due to migraines is 19.6 billion.

SUMMARY OF THE INVENTION This invention is concerned with novel compounds represented by structural formula I: ##STR2## wherein R.sup.2, R.sup.3, R.sup.6, R.sup.7, R.sup.8, R.sup.11, R.sup.12, R.sup.13, A, B, p, Y and Z are hereinafter defined. The invention is also concerned with pharmaceutical

BACKGROUND OF THE INVENTION This invention relates to novel compositions of matter containing optically pure R(+) ondansetron. These novel compositions have potent antiemetic activity and are useful in ameliorating the nausea and vomiting otherwise induced by cancer chemotherapeutic agents and

FIELD OF THE INVENTION This invention relates to magnesium-based compositions for treating migraine headaches, and methods for using the same. BACKGROUND OF THE INVENTION Analgesic compositions comprising magnesium salts have been used to treat a variety of ailments as well as reduce the gastric

FIELD OF THE INVENTION This invention relates to magnesium-based analgesic compositions for treating migraine headaches, and methods for using the same. BACKGROUND OF THE INVENTION Analgesic compositions comprising magnesium salts have been used to treat a variety of ailments as well as reduce the

This invention relates to a method of treatment of migraine, cluster headaches and trigeminal neuralgia, radiation or cytotoxic agent induced nausea and vomiting and/or cardiac arrhythmia in mammals, including humans, and to the use of compounds in the preparation of a medicament for the treatment

This invention relates to a class of 5-membered heterocyclic compounds having at least one heteroatom, which are useful in the treatment of psychotic disorders (e.g. schizophrenia and mania); anxiety; alcohol or drug withdrawal or dependence; pain; gastric stasis; gastric dysfunction (such as occurs

BACKGROUND OF THE INVENTION This invention relates to benzisoxazole derivatives. These compounds have selective 5-HT.sub.4 receptor agonistic activity. The present invention also relates to a pharmaceutical composition, method of treatment and use, comprising the above derivatives for the treatment