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migraine disorders/cannabis
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8 결과
Cannabinoid receptor modulators
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CROSS-REFERENCE TO RELATED APPLICATIONS
This application is a National Stage Application under 35 U.S.C. .sctn.371 of International Application No. PCT/US2010/002360, filed Aug. 27, 2010, which claims priority under 35 U.S.C. .sctn.119(e) to U.S. Provisional Application Nos. 61/275,506, filed Aug.
Cannabinoid receptor modulators
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FIELD OF THE INVENTION
The present invention relates to certain compounds of Formula Ia and pharmaceutical compositions thereof that modulate the activity of the cannabinoid CB.sub.2 receptor. The present invention further relates to certain compounds of Formula Ia and pharmaceutical compositions
Substituted pyrano[2,3-B]pyridine derivatives as cannabinoid-1 receptor modulators
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BACKGROUND OF THE INVENTION
Marijuana (Cannabis sativa L.) and its derivatives have been used for centuries for medicinal and recreational purposes. A major active ingredient in marijuana and hashish has been determined to be .DELTA..sup.9-tetrahydrocannabinol (.DELTA..sup.9-THC). Detailed research
Aralkyl amines as cannabinoid receptor modulators
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BACKGROUND OF THE INVENTION
Marijuana (Cannabis sativa L.) and its derivatives have been used for centuries for medicinal and recreational purposes. A major active ingredient in marijuana and hashish has been determined to be .DELTA.9-tetrahydrocannabinol (.DELTA.9-THC). Detailed research has
Substituted imidazoles as cannabinoid receptor modulators
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SUMMARY OF THE INVENTION
The present invention is concerned with substituted imidazole of the general Formula I:
##STR00001## and pharmaceutically acceptable salts thereof which are antagonists and/or inverse agonists of the Cannabinoid-1 (CB1) receptor and are useful in the treatment, prevention
Substituted imidazoles as cannabinoid receptor modulators
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SUMMARY OF THE INVENTION
The present invention is concerned with substituted imidazole of the general Formula I:
##STR00001## and pharmaceutically acceptable salts thereof which are antagonists and/or inverse agonists of the Cannabinoid-1 (CB1) receptor and are useful in the treatment, prevention
Diphenyl cyclopentyl amides as cannabinoid-1 receptor inverse agonists
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BACKGROUND OF THE INVENTION
Marijuana (Cannabis sativa L.) and its derivatives have been used for centuries for medicinal and recreational purposes. A major active ingredient in marijuana and hashish has been determined to be .DELTA..sup.9-tetrahydrocannabinol (.DELTA..sup.9-THC). Detailed research
Synthetic endogenous cannabinoids analogues and uses thereof
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STATEMENT OF THE INVENTION
The present invention relates to compounds of the general formula (I), to a process for their preparation, to pharmaceutical compositions containing at least one compound of the invention and to the different uses of said compounds.
BACKGROUND OF THE INVENTION
Anandamide
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