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Accelerated Checkpoint Therapy for Any Steroid Dependent Patient With Brain Metastases

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non_invasive_aICP_Tumor

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Primary brain tumors in adults are less common than metastatic tumors. The most frequent are glioblastoma multiforme, metastases, anaplastic astrocytoma, meningioma, pituitary tumors and vestibular schwannoma. 70% of the tumors in adults are supratentorial. The most infratentorial tumors are

Study of Cytolytic Viral Activation Therapy (CVAT) for Recurrent/Metastatic Nasopharyngeal Carcinoma

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1. Introduction to investigational treatment(s) and other study treatment(s) 1.1 Overview of gemcitabine Gemcitabine (29,29-difluoro 29-deoxycytidine, dFdC) which developed from cytosine arabinoside (Ara-C) is an nucleoside analog used as chemotherapy. It was intended as an antiviral drug in

The Value of CE-LUS During Robot-assisted Surgery for Primary Colorectal Cancer

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Title: The value of contrast enhanced laparoscopic ultrasound examination during robot-assisted resection for primary colorectal cancer surgery. Project: The following project evaluates the value of contrast enhanced Laparoscopic Ultrasound examination (CE-LUS) in robot-assisted surgery for CRC. The

Intrathecal Methotrexate for Progressive Multiple Sclerosis: An Open Label Single Arm Study

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Protocol Intrathecal Methotrexate for Progressive Multiple Sclerosis: An Open Label Single Arm Study Introduction Multiple sclerosis (MS) is characterized pathologically by demyelination, axonal loss, and glial scar formation. Clinically, most patients have a relapsing-remitting course of MS (RRMS)

Phase II Trial of Conventional Versus IMRT Whole Brain Radiotherapy for Brain Metastases

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SCHEMA For Patients with MRI Evidence of Brain Metastasis within 1 Month Prior to Registration Prior to Treatment Start Confirmation of patient's insurance coverage prior to receiving study-related procedures to e ensure that treatment with IMRT will not be denied. Radiation Therapy 1. MRI with

Efficacy of Gefitinib for Brain Metastasis of Non-Small Cell Lung Cancer

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Inclusion criteria: 1. Histological or cytological documented stage IV NSCLC. Sputum cytology alone is excluded. 2. Extracerebral lesions show stable disease after first line chemotherapy. Patient has recovered from CTCAE grade 3/4 toxicity. Patients who had never received EGFR-TKI or EGFR

Postoperative Adjuvant Therapy With Recombinant Interferon-Alpha Following Curative Resection of HCC

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1. Background Hepatocellular carcinoma (HCC) is the second commonest cause of cancer death in Hong Kong and the majority are hepatitis B related. Hepatic resection has remained the only therapeutic option that can offer these patients a chance of long-term survival. Although the safety of

Immunochemotherapy for Metastatic Renal Cell Carcinoma

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This is a phase II study, non-randomized in patients with metastatic renal cell carcinoma. The treatment will include: Proleukin (produced by Chiron and supplied by Megapharm Israel Ltd), Roferon A and Xeloda (produced by Roche) and VBL. The treatment will be given in 8-week courses with an interval

Carboplatin Taxol Avastin in Ovarian Cancer (OVCA)

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Ovarian cancer is diagnosed in approximately 26,000 American women each year, and is the leading cause of death from gynecologic cancers. Difficult to detect, the disease typically presents only when advanced. Ovarian cancer is among the most sensitive of solid tumors to chemotherapy. However, the
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