piperidine/hypoxia

The present invention relates to therapeutically active piperidine compounds, a method of preparing the same and to pharmaceutical compositions comprising the compounds. The novel compounds are useful in the treatment of anoxia, traumatic injury, ischemia, migraine and epilepsy. It is well known

The present invention relates to therapeutically active piperidine compounds, a method of preparing the same and to pharmaceutical compositions comprising the compounds. The novel compounds are useful in the treatment of anoxia, ischemia, migraine and epilepsy. It is well known that accumulation of

The present invention relates to therapeutically active piperidine compounds, a method of preparing the same and to pharmaceutical compositions comprising the compounds. The novel compounds are useful in the treatment of anoxia, ischemia, migraine and epilepsy. It is well known that accumulation of

The present invention relate s to therapeutically active piperidine compounds, a method of preparing the same and to pharmaceutical compositions comprising the compounds. The novel compounds are useful in the treatment of anoxia, ischemia, migraine and epilepsy. It is well known that accumulation of

The present invention relates to therapeutically active piperidine compounds, a method of preparing the same and to pharmaceutical compositions comprising the compounds. The novel compounds are useful in the treatment of anoxia, traumatic injury, ischemia, migraine and epilepsy. It is well known

The present invention relates to therapeutically active piperidine compounds, a method of preparing the same, pharmaceutical compositions comprising the compounds and to a method of treating therewith. The novel compounds are useful in the treatment of anoxia, ischemia, migraine and epilepsy. It is

The invention will now be described in further detail with reference to the following examples: Example 1 (-)-trans-4-(-4-fluorophenyl)-3-(3,4-methylenedioxyphenoxymethyl)-1-pentylp iperidine hydrochloride 10g of (-)-trans-4-(-4-fluorophenyl)-3,4-methylenedioxyphenoxymethyl)-piperidine hydrochloride

FIELD OF THE INVENTION This invention relates to weakly basic derivatives of 2-nitroimidazoles (pKa about 8 or greater) and their penultimate chemical precursors that are useful for the non-invasive measurement of cellular hypoxia in normal and cancer tissue by means of positron emission tomography

FIELD OF THE INVENTION The present invention relates to 4-hydroxy-4-methyl-piperidine-1-carboxylic acid(4-methoxy-7-morpholin-4-yl-benzothiazol-2-yl)-amide, which is a compound of formula ##STR00002## and to pharmaceutically acceptable acid addition salts thereof. This compound is generically

The present invention relates to therapeutically active piperidine compounds, a method of preparing the same, pharmaceutical compositions comprising the compounds and to a method of treating therewith. The novel compounds are useful in the treatment of anoxia, ischemia, migraine and epilepsy. It is

The present invention relates to therapeutically active piperidine compounds, a method of preparing the same and to pharmaceutical compositions comprising the compounds. The novel compounds are useful in the treatment of anoxia, ischemia, migraine and epilepsy. It is well known that accumulation of

This invention relates to alkyl and cycloalkylthiophenylalkylaminoalkanols, to the salts of these latter by addition of organic or inorganic acids, and also to the preparation of these compounds. The present invention provides an amino-alcohol having the formula: ##STR2## wherein R.sub.1 represents