Patients will receive daily oral low dose Acetylsalicylic acid (75 mg) starting day 20 of the previous cycle withGonadotrophin releasing hormone agonist (GnRH agonist)

Patients will receive daily oral low dose Acetylsalicylic acid (75 mg) and Low dose prednisolone (10 mg/day) starting day 20 of the previous cycle withGonadotrophin releasing hormone agonist (GnRH agonist).

Infertility

daily oral low dose prednisolone (10 mg/day) :a glucocorticoid

prednisolone

daily oral low dose Acetylsalicylic acid (75 mg) : Antiplatelet agent

Acetyl Salicylic acid

KasralainiH

The Value of Prednisolone With Aspirin Before Embryo Transfer in Intracytoplasmic Sperm Injection (ICSI) Cycles

The Value of Addition of Prednisolone to Acetylsalicylic Acid Prior to Embryo Transfer in Patients With First ICSI Cycles: A Randomized Controlled Trial

Detection of gestational sac , embryo pole and fetal pulsations by transvaginal ultrasound

number of oocytes retrieved during ovum pickup per cycle.

The number of oocytes fertilized by intracytoplasmic sperm injection per cycle.

number of embryos of any grade ( first, second, third or fourth grade) per cycle

embryo quality by grade ( first, second, third or fourth) per cycle.

Detection of 2 gestational sacs with positive fetal poles and pulsations per cycle.

Amira S Dieb

Ob/Gyn Lecturer

Kasr El Aini Hospital

17 patients received continuous medication with salsalate 2g/day after run-in period

17 patients received continuous medication with Placebo 2g/day after run-in period

Non Alcoholic Fatty Liver

Osteo Arthritis

Medicate salsalate 2g/day after run-in period
Check side effect after 1 month and Control dosage (2g/day or 3g/day)
Check side effect after 2 month

Salsalate

Medicate placebo 2g/day after run-in period
Check side effect after 1 month and Control dosage (2g/day or 3g/day)
Check side effect after 2 month

Placebo

Korea University Guro Hospital

The Comparison of Effect Between Salsalate and Placebo in Osteoarthritis With Nonalcoholic Fatty Liver Disease

The Comparison of Effect Between Salsalate and Placebo in Osteoarthritis With Nonalcoholic Fatty Liver Disease: Investigator Initiated Randomized Placebo-controlled Double-blind, Pilot Study

Estimation of salsalate single injection group and placebo injection group

Estimation with treatment-related adverse events as assessed by CTCAE v4.0

Ji Hoon Kim

Associate professor

Kuhnil Pharmaceutical Co., Ltd.

T2DM Patients implanted with a DJBL (Duodenal jejunal Bypass liner, EndoBarrier, GI Dynamics) due to medical reasons.
The subjects were regular in-patients of the Diabetes Center at the Heart and Diabetes Center NRW, Germany and gave informed consent for related procedures and data handling. The subjects had BMI ≥35 kg/m2, T2DM, and a history of frustrated weight loss attempts. Exclusion criteria: history of gastric surgery, gastric or duodenal ulcers, thyroid disorders, gastrointestinal disorders with intestinal resorption dysfunction, therapy with oral anticoagulants, use of acetyl salicylic acid or non-steroidal anti-inflammatory drugs, drug abuse (incl. alcohol), symptomatic cardiovascular disease, renal insufficiency (GFR <50 ml/min), pregnancy or breast feeding.

Blood sampling during study, analysis via ELISA for special markers at study end in one batch, active medical control parameters like HbA1c, cholesterol, hemogram etc. at visits

Type 2 Diabetes Mellitus

Obesity

Implantation of EndoBarrier after medical and patient's decision, Duration of treatment 12 months in maximum, follow up for 4 weeks after Explantation, follow up during treatment by physical examination, ECG control, sampling and analysis of blood parameters, mixed meal tolerance tests only for diagnostic purposes to assess gut hormonal changes and metabolic parameters

DJBL (Duodenal jejunal bypass liner, EndoBarrier)

Herz- und Diabeteszentrum

Metabolic Effects of Duodenal Jejunal Bypass Liner for Type 2 Diabetes Mellitus

Metabolic Effects of Duodenal Jejunal Bypass Liner for the Treatment of Adipose Patients With Type 2 Diabetes Mellitus

weight loss defined as excess weight loss

effect of DJBL on body composition in overweight T2DM patients determined by bioimpedance scaling

salicylic acid/비만증

The Value of Prednisolone With Aspirin Before Embryo Transfer in Intracytoplasmic Sperm Injection (ICSI) Cycles

The Comparison of Effect Between Salsalate and Placebo in Osteoarthritis With Nonalcoholic Fatty Liver Disease

Metabolic Effects of Duodenal Jejunal Bypass Liner for Type 2 Diabetes Mellitus

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