sleepiness/atrophy

Our aim was to determine regional brain atrophy in Parkinson's disease (PD) patients with excessive daytime sleepiness (EDS) using voxel-based morphometry (VBM). From 71 consecutive probable PD patients, nine non-demented and non-hallucinating patients with an Epworth Sleepiness Scale (ESS) ≥ 10 and

BACKGROUND The recent SLEEMSA study that evaluated excessive daytime sleepiness (EDS) in Caucasian patients with multiple system atrophy (MSA) demonstrated that EDS was more frequent in patients (28%) than in healthy subjects (2%). However, the prevalence and determinants of EDS in other ethnic

BACKGROUND Sleep disorders are common in multiple system atrophy (MSA), but the prevalence of excessive daytime sleepiness (EDS) is not well known. OBJECTIVE To assess the frequency and associations of EDS in MSA. METHODS Survey of EDS in consecutive patients with MSA and comparison with patients

Recent observations suggest that levodopa can induce irresistible sleep onset in multiple system atrophy (MSA). Therefore, we assessed sleepiness during a levodopa challenge in 17 MSA compared with 23 Parkinson's disease (PD) patients using the Stanford Sleepiness Scale (SSS). SSS scores during the

BACKGROUND Many patients with Parkinson's disease (PD) report daytime sleepiness. Its etiology, however, is still not fully understood. The aim of this study was to examine if the amount of nigrostriatal dopaminergic degeneration is associated with subjective daytime sleepiness in patients with

OBJECTIVE Central nervous system involvement is one important clinical aspect of myotonic dystrophy type 1 and 2 (DM1 and DM2). We assessed CNS involvement DM1 and DM2 by 3T MRI and correlated clinical and neuocognitive symptoms with brain volumetry and voxel-based morphometry (VBM). METHODS 12

Multiple-system atrophy (MSA) is characterized by progressive autonomic failure with cerebellar, pyramidal and extrapyramidal signs. In MSA patients laryngoscopy often reveals unilateral or bilateral abductor vocal fold palsies. Snoring is very common. However, assessment of sites of obstruction and

The aim of the present study was to assess whether or not there is any correlation between magnetic resonance imaging (MRI) abnormalities and excessive daytime sleepiness (EDS) in a consecutive series of patients with myotonic dystrophy (MD). The influences of nocturnal breathing abnormalities and

Sleepiness, a commonly symptom affecting up to one-fifth of the population chronically, is clearly an important cause of accidents in industry and transport inducing deterioration in performance and attention. The reason for Excessive Daytime Sleepiness (EDS) is either sleep pathology, voluntary

A previous posturographic force platform study verified that human balance deteriorates as a function of time awake (TA). It found that TA can be estimated with +/-2.5 h accuracy using 30 s trial length. For a fast, reliable and convenient sleepiness monitor even better TA estimation accuracy and

OBJECTIVE We examined sleep, daytime sleepiness and the ability to stay awake during the day in patients affected with retinitis pigmentosa (RP), to further delineate the role of photoreceptors in the circadian cycle. METHODS Twelve individuals diagnosed with RP (40 +/- 8 years) And 12 normally

By the end of the first night on a 12h night-shift, wakefulness may have lasted up to 24h since the previous sleep. Although most work situations requiring critical decisions are foreseen and effectively resolved by well trained staff, such wakefulness can produce impairments in dealing with

No data are available regarding the occurrence of sleep disorders in spinal and bulbar muscular atrophy (SBMA). We investigated the sleep-wake cycle in SBMA patients compared with healthy subjects. Nine SBMA outpatients and nine age-matched and sex-matched healthy controls were evaluated. Subjective

OBJECTIVE To assess the diagnostic accuracy of portable polygraphy (PG) for the detection of sleep apnea (SA) in multiple system atrophy (MSA). METHODS Thirty consecutive patients with probable MSA underwent PG (overnight recording of nasal flow, thoracic/abdominal movements and pulse oximetry),