[Composition and antitumor activities of essential oil from the fruits of Dasymaschalon trichophorum].
Raktažodžiai
Santrauka
OBJECTIVE
To study the chemical components and antitumor activities of essential oil from the fruits of Dasymaschalon trichophorum.
METHODS
The essential oil from the fruits of Dasymaschalon trichophorum was extracted by steam-stilling and analyzed by GC-MS. The inhibitory effect of extract of Dasymaschalon trichophorum on SPCA-1,BEL-7402, SGC-7901 and K-562 cell proliferation was assayed using the MTU.
RESULTS
GC-MS result showed that there were 55 peaks and 30 compounds were identified which weighed 74.98%. The major components were nerolidol (19.887%), caryophyllene (16.714%) and beta-myrcene (9.29%). The essential oil exhibited strong antitumor activity against SPCA-1 human tumor cell line with IC50 value of 6.61 microg/mL.
CONCLUSIONS
This experiment provides scientific foundation for further utilization of Dasymaschalon trichophorum.
