Inhibitory effects of stilbenes in Sophora moorcroftiana BENTH ex BAKER on copper ion-induced protein oxidative modification of mouse brain homogenate in vitro.

We present the results of an in vitro investigation of the inhibitory effects of sophorastilbene A and (+)-alpha-viniferin isolated from Sophora moorcroftiana BENTH ex BAKER on copper ion-induced protein oxidative modification. They inhibited copper-induced protein oxidative modification. The order of these stilbenes and mannitol as a hydroxyl radical scavenger was sophorastilbene A > (+)-alpha-viniferin > mannitol.