Journal of Natural Products 2001-Aug
Verbalactone, a new macrocyclic dimer lactone from the roots of Verbascum undulatum with antibacterial activity.
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A novel macrocyclic dimer lactone, named verbalactone, was isolated from the roots of Verbascum undulatum and exhibited interesting antibacterial activity. It is the first time that 1,7-dioxacyclododecane is reported as the ring system of a natural product. The structure and the absolute stereochemistry of the new compound were determined by spectral methods and chemical correlation.