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2 3 benzofuran/uždegimas
Nuoroda įrašoma į mainų sritį
Puslapis 1 nuo 35 rezultatus
Method of treating inflammation and pain using heteramino benzofurans
Straipsnius versti gali tik registruoti vartotojai
Prisijungti Registracija
The invention relates to novel furans, especially benzofuranones of the general formula ##STR2## in which R.sub.1 represents hydrogen or an aliphatic radical, R.sub.2 represents an amino group di-substituted by a divalent hydrocarbon radical, and the aromatic ring A may be additionally substituted,
Benzofuran and benzothiophene derivatives as anti-inflammatory agents
Straipsnius versti gali tik registruoti vartotojai
Prisijungti Registracija
BACKGROUND OF THE INVENTION
1. Field of the Invention
This invention relates to anti-inflammatory and analgesic compounds, especially to certain benzofuran and benzothiophene derivatives, pharmaceutical compositions containing them, methods for their use, and methods for preparing these
Benzofuran-2(3H)-ones used as anti-inflammatory agents
Straipsnius versti gali tik registruoti vartotojai
Prisijungti Registracija
The invention relates to novel lactones, especially benzofuranones of the general formula ##STR2## in which R.sub.1 represents hydrogen or an aliphatic radical, R.sub.2 represents an amino group di-substituted by two monovalent hydrocarbon radicals, and the aromatic ring A may be additionally
Oxalylamino-benzofuran- and benzothienyl-derivatives
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Prisijungti Registracija
The invention relates to Oxalylamino-benzofuran- and benzothienyl-derivatives, processes for their preparation and their use in medicaments.
It is known that the NADPH oxidase of phagocytes is the physiological source to the superoxide radical anion and reactive oxygen species derived therefrom
Protein kinase C modulators. C. indolactam structural-types with anti-inflammatory activity
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Prisijungti Registracija
BACKGROUND
Protein kinase C is an enzyme found in nearly all animal tissues and animal cells that have been examined. Its identity is generally established by its ability to phosphorylate proteins when adenosine triphosphate and phospholipid cofactors are present, with greatly reduced activity when
Benzofuran derivatives
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Prisijungti Registracija
FIELD OF THE INVENTION
The present invention is directed to methods for treating neuroinflammation, neurodegeneration, or degenerative diseases in which mitochondrial dysfunction leads to tissue degeneration.
The invention relates to certain novel compounds having cytoprotective and neuroprotective
Cytoprotective benzofuran derivatives
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Prisijungti Registracija
FIELD OF THE INVENTION
The present invention relates to certain compounds having cytoprotective activity, and particularly to a series of benzofuran derivatives. The invention is also directed to formulations and methods for treating stroke, myocardial infarction and chronic heart failure, as well
Cylopenta[b]benzofuran derivatives and the utilization thereof
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Prisijungti Registracija
The present application relates to novel cyclopenta[b]benzofuran derivatives, processes for their preparation and their use for the manufacture of medicaments, in particular for the prophylaxis and/or therapy of acute or chronic disorders characterized by elevated cellular stress, by local or
Benzofuran derivatives
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Prisijungti Registracija
BACKGROUND OF THE INVENTION
This invention involves certain benzofuran derivatives. These compounds are useful as inhibitors of mammalian leukotriene biosynthesis. As such, these compounds are useful therapeutic agents for treating allergic conditions, asthma, cardiovascular disorders and
Benzofuran derivatives useful as inhibitors of mammalian leukotriene biosynthesis
Straipsnius versti gali tik registruoti vartotojai
Prisijungti Registracija
BACKGROUND OF THE INVENTION
This invention involves certain benzofuran derivatives. These compounds are useful as inhibitors of mammalian leukotriene biosynthesis. As such, these compounds are useful therapeutic agents for treating allergic conditions, asthma, cardiovascular disorders and
6-hydroxy-2(2-hydroxy-4-methoxyphenyl)benzofuran derivatives to inhibit leukotriene biosynthesis
Straipsnius versti gali tik registruoti vartotojai
Prisijungti Registracija
BACKGROUND OF THE INVENTION
This invention involves certain 6-Hydroxy-2-(2-hydroxy-4-methoxyphenyl)benzofuran derivatives. These compounds are useful inhibitors of mammalian leukotriene biosynthesis. As such, they are useful therapeutic agents for treating allergic conditions, asthma, cardiovascular
Benzofuran compound and medicinal composition containing the same
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Prisijungti Registracija
This application is a U.S. national stage of International Application No. PCT/JP2004/007802 filed May 28, 2004.
TECHNICAL FIELD
The present invention relates to a benzofuran compound having a leukotriene (particularly leukotriene B4) inhibitory action and a pharmaceutically acceptable salt thereof.
Benzofuran derivative and pharmaceutical comprising the same as active ingredient
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Prisijungti Registracija
FIELD OF THE INVENTION
The present invention relates to benzofuran derivatives possessing inhibitory activity against 5-lipoxygenase which is one of the lipoxygenase metabolic enzymes involving the arachidonate cascade, and, because of this activity, useful for the treatment and prevention of
Process for the preparation of anti-inflammatory aroylbenzofuran compounds
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Prisijungti Registracija
FIELD OF THE INVENTION
The present invention relates to a simple process for the preparation of anti-inflammatory compounds. Particularly, the invention provides Ru-catalyzed process for regioselective alkylation of aroylbenzofurans with alpha, beta unsaturated esters via C--H activation in suitable
Certain 3-phenyl-benzofuran lower alkanoic acids and esters thereof
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Prisijungti Registracija
The present invention relates to benzofurans and 2,3-dihydrobenzofurans optionally substituted at the 2 position by halogen or lower alkyl, substituted at the 3 position by optionally substituted phenyl, substituted on the 5,6 or 7 position of the benzo ring by a lower alkanoic acid group or a salt,
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