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[Antitumor effect of actinidia chinensis polysaccharide on murine tumor].

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A new polysaccharide compound (ACPS-R) has recently been isolated from the root of Actinidia Chinensis Planch. When given intraperitoneally to the transplantable tumor bearing mice at dose of 75-125 mg/kg, the tumor inhibition rate was more than 88.8% in Ehrilich ascitic cancer (EAC) or ascitic form

Antimutagenic activity of extracts from anticancer drugs in Chinese medicine.

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The antimutagenic activities of extracts of 36 commonly used anticancer crude drugs from Chinese herbs were studied by using the Salmonella/microsomal system in the presence of picrolonic acid or benzo[a]pyrene to test whether they contain direct or indirect antimutagens. Each crude drug was

Actinidia arguta (Hardy Kiwi) Root Extract Exerts Anti-cancer Effects via Mcl-1-Mediated Apoptosis in Cholangiocarcinoma.

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Cholangiocarcinoma (CCA) is a highly aggressive and chemoresistant liver malignancy. Thus, identification of strategies to overcome insensitivity to apoptosis and growth inhibition is a growing focus of research in this malignancy. This study evaluated the potential anti-cancer effects of an ethanol

Inhibition of hardy kiwifruit (Actinidia aruguta) ripening by 1-methylcyclopropene during cold storage and anticancer properties of the fruit extract.

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Hardy kiwifruits (Actinidia arguta) were treated with 20 μl/l 1-methylcyclopropene (1-MCP) for 16 h at 10 °C and subsequently stored at 1 ± 0.5 °C. Anticancer properties of the fruit extracts were tested against five different human cancer cells. The hardy kiwifruits, without 1-MCP treatment, showed

[Experimental study on the antitumor effects of extracts from roots of Actinidia indochinensis in carcinoma cell lines].

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OBJECTIVE To observe rhe effects of extracts from roots of Actinidia indochinensis on the growth inhibition in carcinoma cell lines. METHODS The growth inhibition was analyzed by MTT, cell colony and cell growth curve measurement in the stomach carcinoma SGC7901, lymphocytic leukemia L1210, lymphoid

[Anti-tumor mechanism of active components from extract of Actinidia rufa root].

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OBJECTIVE To observe effect and mechanism of n-Butanol lysate of alcohol extracts from Actinidia rufa root (monomer of R6,R8). METHODS Tunel, Wright's stain with Giemsa's stain dyeing, and Hoechst 33258-PI double dyeing assay were used to detect the apoptosis of SGC7901 tumor cells treated with R6,

Antioxidant and antitumor activities of water extracts from the root of Actinidia kolomikta.

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The genus of Actinidia is widely distributed throughout the Asian continent. Specific Actinidia species have been used as health foods and medical products for cancer treatment. Actinidia kolomikta is a species of wild plant that grows in the northern part of Indochina. However, few studies on its

Preliminary investigation of catalytic, antioxidant, anticancer and bactericidal activity of green synthesized silver and gold nanoparticles using Actinidia deliciosa.

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Herein we report a rapid low cost one step green synthetic method using Actinidia deliciosa fruit extract for preparation of stable and multifunctional silver and gold nanoparticles. The synthesized nanoparticles were successfully used as green catalysts for the reduction of 4-nitrophenol (4-NP) and

[Study on anti-tumor effect of extractions from roots of Actinidia deliciosa].

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OBJECTIVE To study the anti-tumor effect of ADEE and ADBE in mice. METHODS The models of S180 entity tumor mice and H22 bearing tumor mice were established to observe the effect of ADEE and ADBE on inhibiting S180 entity tumor growth and prolonging life time of H22-mice, and the effect on spleen and

Antitumor and immunomodulatory activity of polysaccharides from the roots of Actinidia eriantha.

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OBJECTIVE The roots of Actinidia eriantha Benth (Actinidiaceae) have been used for cancers in the Chinese folk medicine. The present study aimed at evaluating the antitumor potentials of the polysaccharides from the roots of Actinidia eriantha and elucidating their immunological mechanisms by

Anticancer and anti-angiogenic activities of extract from Actinidia eriantha Benth root.

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BACKGROUND The roots of Actinidia eriantha Benth (AER) are commonly used traditional folk medicine for the treatment of gastric carcinoma, nasopharyngeal carcinoma, and breast carcinoma. Besides, the anti-proliferative and immunomodulatory effects of AER polysaccharides on tumor-bearing mice have

LC-MS-MS determination and pharmacokinetic study of the novel anti-tumor candidate drug TEOA in rats.

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2α, 3α, 24-Trihydroxyurs-12-en-28-oic acid (TEOA) is a prominent ursane-type triterpenoid isolated from the root of Actinidia deliciosa, which has numerous pharmacological activities. To date, there is no report on the pharmacokinetic characterization of TEOA in biological samples. A specific,

[Experimental study on antitumor effects of extracts from Actinidia argutaor].

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OBJECTIVE To observe the inhibitory effect of extract from Actinidia argutaor on in vivo and in vitro carcinomata, and explore its mechanism. METHODS The in vivo S180 and H22 model were used to observe the effect of A. argutaor on inhibitory rate of carcinomata, organ relative weight of spleen and

2β, 3β, 23-trihydroxy-urs-12-ene-28-olic acid (TUA) isolated from Actinidia chinensis Radix inhibits NCI-H460 cell proliferation by decreasing NF-κB expression.

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A natural ursolic compound, 2β, 3β, 23-trihydroxy-urs-12-ene-28-olic acid (TUA) was isolated from the root of Actinidia chinensis Planch (A. chinensis Radix). Since a large number of triterpenoid compound has marked anticancer effects toward various types of cancer cell lines in vitro, this study

Isolation and Identification of Endophytic Fungi from Actinidia macrosperma and Investigation of Their Bioactivities.

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Endophytic fungi from the Chinese medicinal plant Actinidia macrosperma were isolated and identified for the first time. This was the first study to evaluate their cytotoxic and antitumour activities against brine shrimp and five types of tumour cells, respectively. In total, 17 fungal isolates were

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