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actinomycin d/karščiavimas
Nuoroda įrašoma į mainų sritį
Puslapis 1 nuo 104 rezultatus
Multiple adjuvant therapy on a murine fibrosarcoma: actinomycin-D, X-irradiation and local tumor hyperthermia.
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The tumoricidal activities of single dose x-irradiation (RAD) and concomitant Actinomycin D (AMD) with or without local tumor hyperthermia (LTH) on an in vivo Methylcholanthreme-induced fibrosarcoma (Meth-A) are described. The addition of LTH enhanced the actions of AMD, RAD and AMD + RAD; the
Protective effect of hyperthermia against the cytotoxicity of actinomycin D on Chinese hamster cells.
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Hyperthermia is being tested as an adjuvant to chemotherapy for clinical use. We elected to study the interaction of heat at 43 degrees C with actinomycin D (AMD) (0.5 microgram/ml) in tissue culture using plateau phase Chinese hamster cells. The simultaneous administration of 43 degrees C and AMD
Increased uptake and prolonged retention of actinomycin D by concomitant hyperthermia related to cytotoxic enhancement.
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We investigated the possible mechanisms of hyperthermic enhancement of actinomycin D (AMD) cytotoxicity in a neoplastic cell line. The hyperthermic enhancement of AMD cytotoxicity depended on both the temperature and the sequence of the administration. The percentage survival of simultaneous
The effect of hyperthermia alone or in combination with actinomycin D on the RNA metabolism of solid tumors in children.
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The incorporation of 3H-uridine into the RNA was studied under normothermia 37 degrees C/120 min, hyperthermia 42.5 degrees/120 min, and both in combination with Actinomycin D by an autoradiographic in vitro method in 19 solid tumors of children: 6 Wilms' tumors, 5 neuroblastomas, 4 osteogenic
G2 block in Chinese hamster cells induced by x-irradiation, hyperthermia, cycloheximide, or actinomycin-D.
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[Postradiation DNA repair in mammalian cells in combined exposure to hyperthermia, 8-bromocaffeine and actinomycin D].
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Effect of actinomycin D on protein synthesis in murine leukaemia cells after hyperthermia.
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Colorado tick fever virus in cell culture. II. Physical and chemical properties.
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Trent, Dennis W. (University of Oklahoma School of Medicine, Oklahoma City), and L. Vernon Scott. Colorado tick fever virus in cell culture. II. Physical and chemical properties. J. Bacteriol. 91:1282-1288. 1966.-Heat-inactivation kinetics for Colorado tick fever (CTF) virus grown in L cells
Control by hyperthermia of ornithine decarboxylase in Ehrlich ascites tumor cells.
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The effect of hyperthermia on the activity and the messenger RNA levels of ornithine decarboxylase (ODC), which has a rapid rate of turnover in cultured cells, was studied in Ehrlich ascites tumor cells. When the cells were incubated at 42 degrees C, elevation of ODC activity by a change of the
Etoposide, methotrexate, actinomycin D, cyclophosphamide, and vincristine for the treatment of metastatic, high-risk gestational trophoblastic disease.
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OBJECTIVE
To evaluate the efficacy and toxicity of a regimen of etoposide, methotrexate, actinomycin D, cyclophosphamide, and vincristine in patients with metastatic, high-risk gestational trophoblastic tumors.
METHODS
Twelve women with metastatic gestational choriocarcinoma received 64 treatment
Effects of cytostatic drugs and 40.5 degrees C hyperthermia on human clonogenic tumor cells.
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A tumor colony-forming assay was used to investigate the effect of 40.5 degrees C hyperthermia and drugs on the colony-forming ability of human clonogenic tumor cells. In order to be able to perform repeated incubations with identical tumor material, specimens were used that were augmented in the
Adjuvant recombinant thrombomodulin therapy for hepatopathy induced by vincristine, actinomycin D, and cyclophosphamide in pediatric rhabdomyosarcoma: A case report.
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Hepatopathy induced by vincristine, actinomycin D and cyclophosphamide (VAC) is a potentially lethal complication of VAC chemotherapy for pediatric malignancy, which is managed by conventional anticoagulation and liver-supporting treatment alone. We report a case of VAC-induced hepatopathy with
Adjuvant vinblastine, actinomycin D, bleomycin, cyclophosphamide and cis-platinum chemotherapy regimen with and without maintenance in patients with resected stage IIB testis cancer.
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A total of 42 patients with stage IIB nonseminomatous germ cell tumors of the testis after orchiectomy and retroperitoneal lymph node dissection received adjuvant chemotherapy with the modified vinblastine, actinomycin D, bleomycin, cyclophosphamide and cis-platinum regimen. Of the patients 29 had
Synergistic cell killing by antitumor agents and hyperthermia in cultured cells.
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The effects of treatment with several antitumor agents in combination with hyperthermia (42 degrees and 43 degrees) on the cell survival of cultured mouse leukemia L5178Y and mammary carcinoma FM3A cells were studied by following clonal growth in a soft-agar medium. L5178Y cells were more
[Effect by proliferation kinetics of malignant tumors of children of hyperthermia].
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Embryonal tumors (21 Wilms' tumors, 11 neuroblastomas, 9 rhabdomyosarcomas) and 16 sarcomas of the skeleton of childhood were studied with an autoradiographic in vitro method according to the responsibility to hyperthermia 42.5 degrees C/120 min, to Cyclophosphamide, to Doxorubicin, and to
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