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actinomycin d/seizures
Nuoroda įrašoma į mainų sritį
Puslapis 1 nuo 22 rezultatus
[Electroencephalographic study of convulsions caused by actinomycin D injected into the cerebrospinal fluid of cats].
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[A physiologic and morphologic study of the effect of actinomycin D on the genesis of audiogenic epileptic seizures in rats].
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[Comparative study of the convulsion provoking activity of actinomycin D and methionine sulfoximine injected into the cerebrospinal fluid of dogs].
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Glycogen particles in methionine sulfoximine epileptogenic rodent brain and liver after the administration of methionine and actinomycin D.
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Rats and mice were submitted either to the convulsant methionine sulfoximine (MSO) alone or to MSO combined with actinomycin D or methionine respectively. Twenty-four hours after the intraperitoneal administration of these compounds, the animals were killed and tissue samples were prepared for
Actinomycin D suppresses the protective effect of dexamethasone in rats affected by global cerebral ischemia.
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Simultaneous occlusion of both common carotid arteries in female Sprague-Dawley CFY rats produced characteristic symptoms of global cerebral ischemia, such as staggering, circling, convulsions, followed by coma and death. A close correlation existed among these symptoms and the elevation of water
Expression of seizure-related PTZ-17 is induced by potassium deprivation in cerebellar granule cells.
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The aim of this study was to identify changes in gene expression during neuronal apoptosis using the differential display (DD) technique. Potassium deprivation was used to induce neuronal apoptosis in cultured rat cerebellar granule cells. DD analysis of about 1600 transcripts resulted in 8 cDNA
The IVADo regimen--a pilot study with ifosfamide, vincristine, actinomycin D, and doxorubicin in children with metastatic soft tissue sarcoma: a pilot study of behalf of the European pediatric Soft tissue sarcoma Study Group.
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BACKGROUND
The role of doxorubicin (Doxo) as part of multidrug regimens used to treat children with soft tissue sarcoma (STS) is controversial. To evaluate the feasibility of combining Doxo with the well established ifosfamide, vincristine, and actinomycin D (IVA) regimen, the Italian STS Committee
The management of brain metastasis in nonseminomatous germ cell tumours.
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OBJECTIVE
To review our experience of patients with brain metastases from nonseminomatous germ cell tumours (NSGCTs) and to indicate important clinical observations.
METHODS
Between 1990 and 1996, 167 patients with metastatic NSGCT were treated in our department; 11 had brain metastases (eight with
Transcriptional activation of ornithine decarboxylase in adult and neonatal hippocampal slices.
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Ornithine decarboxylase (ODC) is the rate-limiting enzyme in polyamine synthesis and is regulated by both transcription-dependent and transcription-independent mechanisms. We compared the effects of asparagine, an amino acid previously shown to increase ODC activity in adult hippocampal slices, on
N-methyl-D-aspartate receptor dependent transcriptional regulation of two calcium/calmodulin-dependent protein kinase type II isoforms in rodent cerebral cortex.
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Alpha Calcium/calmodulin-dependent protein kinase type II (CaMKII-alpha) expression is regulated in an activity-dependent manner, but it is not known whether other CaMKII isoforms (beta, delta, and gamma) are similarly regulated. We examined the activity-dependent regulation of these CaMKII isoforms
[Clinical characteristics analysis of children with reversible posterior leukoen-cephalopathy syndrome during the treatment of hematological tumor].
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OBJECTIVE
To analyze the clinical characteristics of patients with hematological tumor or disease before and after reversible posterior leukoen-cephalopathy syndrome (RPLS).
METHODS
Five patients were both from Peking University First Hospital Pediatric Hematology-oncology Department in the period
Glycogen content and fructose-1, 6-biphosphatase activity in methionine sulfoximine epileptogenic mouse brain and liver after protein synthesis inhibition.
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Mice given intraperitoneal injections of methionine sulfoximine (MSO) (100 mg/kg body weight) showed tonic-clonic seizures 7 to 8 h later. The protein synthesis inhibitors actinomycin D and cycloheximide, when combined with MSO delayed the onset of seizures. Methionine completely abolished the
Gestational Trophoblastic Neoplasia with Gum Metastasis: A Case Study and Literature Review
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Gestational trophoblastic neoplasia (GTN) is an uncommon group of pregnancy-related malignancies. Delayed diagnosis is a prognostic factor for worse outcome. GTN is even harder to diagnose if the site of metastasis is uncommon. The reported case is a 27-year-old
Reversible posterior leukoencephalopathy syndrome: report of three cases.
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Reversible posterior leukoencephalopathy syndrome is characterized clinically by headache, abnormalities of mental status and visual perception, and seizures. Despite its diverse causes, common precipitating factors are defined as abrupt elevations of blood pressure, renal decompensation, fluid
Differential regulation of the nerve growth factor and brain-derived neurotrophic factor genes in L929 mouse fibroblasts.
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Nerve growth factor (NGF) and brain-derived neurotrophic factor (BDNF) are structurally related survival and differentiation factors for distinct sets of peripheral and central neurons. The regulation of NGF gene expression has been extensively studied in L929 mouse fibroblasts. L929 cells also
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