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androsace/priešvėžiniai vaistai
Nuoroda įrašoma į mainų sritį
4 rezultatus
Different anticancer effects of Saxifragifolin A on estrogen receptor-positive and estrogen receptor-negative breast cancer cells.
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BACKGROUND
Breast cancer is the leading cause of cancer-related death among women worldwide. For treating breast cancer, numerous natural products have been considered as chemotherapeutic drugs.
OBJECTIVE
The present study aims to investigate the apoptotic effect of Saxifragifolin A (Saxi A)
Different apoptotic effects of saxifragifolin C in human breast cancer cells.
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Breast cancer is currently the most common form of cancer affecting women. Recent studies have reported that triterpenoid saponins isolated from Androsace umbellata exhibit anti-proliferative effects in several types of cancer cells. However, the cytotoxic effect of saxifragifolin C (Saxi C) on
Saxifragifolin B from Androsace umbellata induced apoptosis on human hepatoma cells.
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Bioassay-guided phytochemical study of Androsace umbellata led to the successful isolation of saxifragifolin B (SB) for the first time. The anti-tumor effect of SB was firstly reported that it was shown to have potent cytotoxicity on human hepatoma HepG2 cells with IC50 value of 11.9 microM at 24 h.
Afrocyclamin A, a triterpene saponin, induces apoptosis and autophagic cell death via the PI3K/Akt/mTOR pathway in human prostate cancer cells.
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BACKGROUND
Afrocyclamin A, an oleanane-type triterpene saponin, was isolated from Androsace umbellata which used as a traditional herbal medicine.
OBJECTIVE
This study aimed to explore the anticancer activity of afrocyclamin A on human prostate cancer cells in vitro as well as in
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