Puslapis 1 nuo 51 rezultatus
BACKGROUND OF THE INVENTION
1. Field of the Invention
This invention relates to compounds, compositions and methods useful in treating symptoms of immunological and non-immunological disorders such as allergy, inflammation, shock or other disorders wherein arachidonate metabolites are implicated.
2.
BACKGROUND OF THE INVENTION
This invention relates to non-steroidal anti-inflammatory agents, such as are useful for the treatment of arthritis.
SUMMARY OF THE INVENTION
In general, the invention features in one aspect compounds having the general formula ##STR4## wherein X is an alkyl group (e.g.,
CROSS-REFERENCE TO RELATED APPLICATIONS
Not Applicable.
STATEMENT REGARDING FEDERALLY SPONSORED RESEARCH OR DEVELOPMENT
Not Applicable.
INCORPORATION BY REFERENCE OF MATERIAL SUBMITTED ON A COMPACT DISC
Not Applicable.
TECHNICAL FIELD
The present invention relates to generally to anti-inflammatory
BACKGROUND OF THE INVENTION
The present invention is directed toward pyrazolopyrimidine (Formula 1) and pyrimidinyl (Formula 2) bisphosphonic esters, acids, and their pharmaceutically acceptable salts which are useful as anti-inflammatories and anti-arthritic agents.
The present compounds, unlike
BRIEF SUMMARY OF THE INVENTION
This invention relates to a new and useful anti-arthritic preparation, and particularly, to an anti-arthritic preparation comprising a combination of anti-inflammatory agents, both nonsteroidal and steroidal, and a skeletal muscle relaxant. More particularly, the
BACKGROUND OF THE INVENTION
1. Field of the Invention
The present invention relates to .alpha.-arylcarbamoyl cyanoacetic acid derivatives active as anti-inflammatory and anti-arthritic agents, to their use in the treatment of inflammatory or arthritic conditions, and to pharmaceutical compositions
BACKGROUND OF THE INVENTION
Within the past few years, a new class of non-hormonal anti-inflammatory agents, namely, certain 5-aroyl-1-loweralkylpyrrole-2-acetic acid derivatives, have been reported. Due to their anti-inflammatory activity, such derivatives are indicated for the inflammation and
FIELD OF THE INVENTION
This invention provides a new use of acids, esters, and salts of arylmethylphosphonate, phosphonic acids and their derivatives as anti-inflammatory and antiarthritic agents.
BACKGROUND OF THE INVENTION
Among the various phosphonate derivatives known in the art are the
BRIEF SUMMARY OF THE INVENTION
This invention relates to new and useful combinations of non-steroidal anti-inflammatory agents and certain anti-arthritic (and also anti-inflammatory) agents and their tautomeric forms which may be represented by the following structural formulae: ##STR1## wherein X
BRIEF SUMMARY OF THE INVENTION
This invention relates to new and useful combinations of non-steroidal anti-inflammatory agents and certain anti-arthritic (and also anti-inflammatory) agents and their tautomeric forms which may be represented by the following structural formulae: ##STR1## wherein X
BRIEF SUMMARY OF THE INVENTION
This invention relates to new and useful combinations of non-steroidal anti-inflammatory agents and certain anti-arthritic (and also anti-inflammatory) agents and their tautomeric forms which may be represented by the following structural formulae: ##STR1## wherein X
FIELD OF THE INVENTION
This invention relates in general to a preparation having anti-inflammatory, and particularly anti-arthritic, activity which is a lipid extract of mussels, including the New Zealand green lipped mussel, Perna canaliculus, and the blue mussel Mytilus edulis.
BACKGROUND OF THE
FIELD OF THE INVENTION
This invention relates in general to a preparation having anti-inflammatory, and particularly anti-arthritic, activity which is a lipid extract of mussels, including the New Zealand green lipped mussel, Perna canaliculus, and the blue mussel Mytilus edulis.
BACKGROUND OF THE
BACKGROUND OF THE INVENTION
The present invention is directed toward phosphonoacetic esters, acids, and their pharmaceutically acceptable salts which are characterized by (Formula I) and which are useful as anti-inflammatories and anti-arthritic agents.
The present compounds are useful in humans and
BACKGROUND OF THE INVENTION
The present invention is directed toward phosphonoacetic esters, acids, and their pharmaceutically acceptable salts which are characterized by (Formula I) and which are useful as anti-inflammatories and anti-arthritic agents.
The present compounds are useful in humans and