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arthritis/triglyceride

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Methotrexate Versus Secukinumab Safety in Psoriasis Patients With Metabolic Syndrome

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A prospective, non-randomized controlled open trial in psoriasis patients with metabolic syndrome was conducted between January 2019 and May 2020. Inclusion criteria were age ≥ 18 years, being affected by moderate to severe chronic plaque psoriasis and concomitant metabolic syndrome and being

Pharmacokinetics of Omega-3 Monoglycerides

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The growing presence on the North American as well as European market of food products enriched with fish oil as a source of polyunsaturated fatty acids (PUFA) omega-3 in the diet requires evaluation and comment. Research exploring health influence of the consumption of fish oil started in 1990

Investigating Racial Differences in Diet Benefits for Knee Osteoarthritis

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A telephone screening interview will be used to assess each participant's OA status and assessment of the reported duration of knee OA, current and past treatments, comorbid conditions, current medication use, dietary conditions and other exclusion criteria. Eligible, participants will be invited to

Fish Oil in Total Hip Replacement Randomized Clinical Trial

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Introduction/Purpose Fish oil (Omega-3 fatty acid) is commonly used by patients as a natural anti-inflammatory to decrease joint pain from arthritis. Furthermore, fish oil has been found to decrease the risk of coronary artery disease, decrease mild hypertension, prevent cardiac arrhythmias and

Fibromyalgia and Olive Oil

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Aim: The goal of the present study is to investigate the effects of two olive oils with different antioxidant content on cardiovascular risk factors (blood-coagulation parameters, platelet indices, red blood cell count, inflammatory markers, lipid profile, nitric oxide and cortisol) in patients

PsA T2T Statin Trial on Carotid and Coronary Atherosclerosis

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Treatment protocol This is a 1-year prospective, hospital-based, open-label, randomized, controlled trial. The trial comprised two arms. Group 1 will receive T2T strategy together with rosuvastain 20mg daily (T2T-statin group). Group 2 will receive T2T strategy only (T2T-only group). The method of

Cardiovascular Profiles in Rheumatoid Arthritis

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Patient Selection: Screen ~400 Rheumatoid Arthritis (RA) patients followed in Centro Hospitalar do Porto outpatient clinic. All RA patients with regular follow-up will be potentially included. The investigators also aim to enrol age-matched controls for biomarker comparison. Experimental

Do Obese Patients With Primary Knee Osteoarthritis Benefit From a Single Bout of Moderate Intensity Aerobic Exercise?

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Study population: This is an observational study a cohort of sedentary Egyptian patients included thirty four obese patients role diagnosed with primary human knee joint OA according to the criteria of the American College of Rheumatology (ACR)( 8).were selected from those attending the outpatient

National Unified Renal Translation Research Enterprise - Chronic Kidney Disease

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3,000 participants will be recruited from nephrology clinics at multiple participating centres (planned to start with 11). 100 control participants (without CKD) will be recruited from among hospital staff members, people attending diabetes clinics and the general public via advertisements placed in

Microvascular Dysfunction in Obesity

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Twenty-five sedentary class 2 and above obese [body mass index (BMI) >35 kg/m2, waist circumference >40 inches (men) or >35 inches (women)] men and women (18-45 yrs) will participate in these experiments. Individuals under 18 years of age will not be investigated due to the invasive nature of the

Gut Microbiomes in Patients With Metabolic Syndrome

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There is mounting evidence that the gut microbiome plays a vital role in health and wellbeing. In particular, population-association and mouse model studies have demonstrated that gut bacteria can be reproducibly linked to obesity and diabetes. There is, however, a lack of progress in translating

ObeSity Related Colorectal Adenoma Risk

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Bowel cancer, or colorectal cancer (CRC), is the second most common cancer affecting both men and women in England. The majority of CRCs develop from a pre-cancerous type of growth in the bowel called an adenoma. Detecting and removing these adenomas is important in reducing CRC risk. A study which

The Effect of Prednisone on Atherogenesis as Studied in the Macrophage Foam Cell Formation Model System.

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The Effects of Melatonin on Elevated Liver Enzymes During Statins Treatment

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Introduction Statins are widely used in the treatment and prevention of lipid metabolism disorders. They are generally well tolerated but not devoid of side effects. These include, among others, muscular symptoms, arthritis, headaches, gynecomastia. Myositis and rhabdomyolysis associated with

Functional Outcomes of Stay Strong Stay Healthy Program

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Participants will perform resistance exercise for 8 weeks and measurements (anthropometric, electromyography, pulse wave velocity, strength test, dual x-ray absorptiometry, blood enzymes/hormones, and sleep, diet, memory surveys) will be performed pre- and post-exercise program.
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