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aspartate amino transferase/nekrozė
Nuoroda įrašoma į mainų sritį
Puslapis 1 nuo 55 rezultatus
Dose-time effect of isoproterenol on aspartate amino-transferase and necrosis of the rat heart.
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Effect of hyperoxia on liver necrosis induced by hepatotoxins.
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We have tested the effects of hyperbaric oxygen on necrosis of rat liver induced by the administration of several toxins. The extent of liver necrosis was determined 24 h after the administration of the toxins by measurement of serum levels of alanine and aspartate amino-transferases and by
Metal concentrations and histopathological changes in goats (Capra hircus) reared near an industrial area of West Bengal, India.
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The present investigation was performed to assess the concentrations of four heavy metals-lead (Pb), cadmium (Cd), copper (Cu), and cobalt (Co)-in goats reared in the vicinity of an industrial area of West Bengal, India, including soil, water, and feedstuffs; tissues of liver, kidney, lung, spleen,
Effect of administration of carnitine on the severity of myocardial infarction induced by isoproterenol in rats.
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The effect of administration of carnitine on the severity of myocardial infarction in rats induced by isoproterenol was studied by following histopathological and biochemical parameters. Carnitine afforded partial protection against myocardial infarction. Serum aspartate amino transferase (GOT) and
Protective effect of Piper longum Linn. on monosodium glutamate induced oxidative stress in rats.
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Protective effect of ethanol extract of Piper longum Linn. against monosodium glutamate (MSG) induced toxicity was studied. Rats, orally administered with MSG at a dose of 8 mg/g body weight for 20 consecutive days, showed an increase in liver weight and rate of lipid peroxidation. Glutathione (GSH)
Role of transient receptor potential cation channel subfamily M member 2 in hepatic ischemia-reperfusion injury in the mouse and the underlying mechanisms
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Objectives: To investigate the role of transient receptor potential cation channel subfamily M member 2 (TRPM2) in hepatic ischemia-reperfusion injury of mouse (HIRI) and the possible mechanisms.
Methods:
The effects of Ipomoea carnea on goats and sheep.
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The clinical signs and lesions of Nubian goats and Desert sheep orally dosed with fresh and dry leaves and stems of Ipomoea carnea at 2.5, 5 and 10 g/kg/day were studied. The signs of Ipomoea poisoning were inappetence, depression, weakness of the hind limbs, dyspnea, staggering, and pallor of the
Glycine prevents alcohol-induced liver injury by decreasing alcohol in the rat stomach.
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OBJECTIVE
Inactivation of Kupffer cells prevents alcohol-induced liver injury, and hypoxia subsequent to a hypermetabolic state caused by activated Kupffer cells probably is involved in the mechanism. Glycine is known to prevent hepatic reperfusion injury. The purpose of this study was to determine
Biochemical alterations induced by a new phosphorothionate (RPR-II) in tissues of male and female rats.
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This study was conducted to investigate the effect of a new phosphorothionate, the methyl ester of 2-butenoic acid-3-diethoxy phosphinothioyl (RPR-II) on membrane bound target enzymes aspartate amino transferase (ASAT), alanine amino transferase (ALAT) and RBC acetylcholinesterase (AChE) in
Hepatoprotective constituents of Torilis radiata Moench (Apiaceae).
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An investigation of the aqueous ethanolic extract (AE) of the aerial parts of Torilis radiata Moench yielded two triterpenes (lupeol acetate (1) and α-amyrin (2)), a sterol (spinasterol (3)) from its n-hexane fraction (HF), a flavone (acacetin (4)), a coumarin (scopoletin (5)), a phenolic acid
[Effects of magnesium lithospermate B on D-galactosamine induced rat liver injury].
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To investigate the effective ingredients of Salvia miltiorrhizae on anti-liver injury, the water soluble component of the above drug, magnesium lithosperamate B, was used to conduct the experimental treatment of acute liver injury by D-galactosamine (10 mg/kg body weight, orally). The results showed
Ascorbic acid protects guinea pigs from acute aflatoxin toxicity.
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These studies were conducted to investigate whether ascorbic acid protected guinea pigs from aflatoxin B1 (AFB1) toxicity. Young guinea pigs, fed either 0 (AA) or 25 mg (25 AA) or gavaged 300 mg ascorbic acid (300 AA) per day for 21 days, were gavaged with the LD50 dose of AFB1 on the 22nd day.
Urinary trypsin inhibitor protects against liver injury and coagulation pathway dysregulation induced by lipopolysaccharide/D-galactosamine in mice.
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Urinary trypsin inhibitor (UTI), a serine protease inhibitor, has been widely used for patients with inflammatory disorders including disseminated intravascular coagulation, shock, and pancreatitis in Japan. Our recent studies using UTI-null (-/-) mice have shown that UTI protects against systemic
A mouse model for luminal epithelial like ER positive subtype of human breast cancer.
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BACKGROUND
Generation of novel spontaneous ER positive mammary tumor animal model from heterozygous NIH nude mice.
METHODS
Using brother-sister mating with pedigree expansion system, we derived a colony of heterozygous breeding females showing ER-Positive tumors around the age of 6 months. Complete
Effect of aspartate and glutamate on experimental myocardial infarction in rats.
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Cardiac necrosis was produced in rats by administering isoproterenol sulphate (85 mg/kg, sc for 4 days). The myocardial damage was proved by observing the elevated levels of serum aspartate amino-transferase, lactate dehydrogenase and creatine phosphokinase and the changes were confirmed by
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