Atrophy / edema

Diagnostic method and system for detecting early age macular degeneration, maculopathies and cystoid macular edema post cataract surgery

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FIELD OF THE INVENTION This invention relates to a method and system for using a calibrated retinoscope and parallel light technique to estimate the reflection of melanin particles in the retina to detect macular degeneration prior to physical symptoms. BACKGROUND OF THE INVENTION In the Western

Diagnostic method and system for detecting early age-related macular degeneration, maculopathies and cystoid macular edema post cataract surgery

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FIELD OF THE INVENTION This invention relates to a method and system for using a calibrated retinoscope and parallel light technique to estimate the reflection of melanin particles in the retina to detect macular degeneration prior to physical symptoms. BACKGROUND OF THE INVENTION In the Western

Treatment of macular edema

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BACKGROUND OF THE INVENTION Macular edema is swelling within the retina within the critically important central visual zone at the posterior pole of the eye. An accumulation of fluid within the retina tends to distract the neural elements from one another and from their local blood supply, creating

Compositions and methods for treating macular edema

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FIELD OF THE INVENTION The present disclosure generally relates to compositions and methods for the prevention, stabilization and/or treatment of macular edema, in particular that results from central retinal vein occlusion (CRVO), branch retinal vein occlusion (BRVO), age related macular

Norrin regulation of cellular production of junction proteins and use to treat retinal vasculature edema

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FIELD OF THE INVENTION The present invention is directed generally to methods of regulating VE-cadherin and claudin gene expression in retinal tissue by applying to such tissue norrin protein; and in particular, to produce additional cellular production of VE-cadherin and claudin-5 in retinal

Norrin regulation of cellular production of junction proteins and use to treat retinal vasculature edema

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FIELD OF THE INVENTION The present invention is directed generally to methods of regulating VE-cadherin and claudin gene expression in retinal tissue by applying to such tissue norrin protein; and in particular, to produce additional cellular production of VE-cadherin and claudin-5 in retinal

Methods and compositions for treatment of macular and retinal disease

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FIELD OF THE INVENTION The present invention relates to methods and compositions for treatment and prevention of disease, and in particular embodiments, disorders of the eye. In an embodiment, the present invention describes linking therapeutic compounds to xanthophyll carotenoids to enhance

Quinoline derivatives and their use as tyrosine kinase inhibitors

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FIELD OF THE INVENTION The present invention relates to quinoline derivatives and to the use thereof in therapy. More particularly, the present invention relates to quinoline derivatives for the treatment of cancer, diabetic retinopathy, age-related macular degeneration, inflammation, stroke,

Quinoline derivatives and their use as tyrosine kinase inhibitors

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FIELD OF THE INVENTION The present invention relates to quinoline derivatives and to the use thereof in therapy. More particularly, the present invention relates to quinoline derivatives for the treatment of cancer, diabetic retinopathy, age-related macular degeneration, inflammation, stroke,

Glucocorticoids attached to nitrate esters via an aromatic linker in position 21 and their use in ophthalmology

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The invention relates to nitrooxy derivatives of steroids, methods for their preparation, pharmaceutical compositions containing these compounds, and methods of using these compounds and compositions for treating ocular diseases, in particular diabetic macular edema, diabetic retinopathy, macular

Glucocorticoids attached to nitrate esters via an aromatic linker in position 21 and their use in ophthalmology

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The invention relates to nitrooxy derivatives of steroids, methods for their preparation, pharmaceutical compositions containing these compounds, and methods of using these compounds and compositions for treating ocular diseases, in particular diabetic macular edema, diabetic retinopathy, macular

Therapeutic treatment for VEGF related ocular diseases

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BACKGROUND OF THE INVENTION 1. Field of the Invention The present invention is broadly directed to a method for inhibiting endothelial cell growth and capillary permeability associated with vascular endothelial growth factor (VEGF), e.g., the increased cell growth and permeability induced by VEGF

Tyrosine kinase inhibitors

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BACKGROUND OF THE INVENTION The present invention relates to compounds which inhibit, regulate and/or modulate tyrosine kinase signal transduction, compositions which contain these compounds, and methods of using them to treat tyrosine kinase-dependent diseases and conditions, such as angiogenesis,

Polymorphs with tyrosine kinase activity

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BACKGROUND OF THE INVENTION The present invention relates to active polymorphs of 4-[2-(5-cyano-thiazol-2-ylamino)-pyridin-4-ylmethyl]-piperazine-1-carboxyl ic acid methylamide, which inhibit, regulate and/or modulate tyrosine kinase signal transduction, compositions which contain these polymorphs,

Substituted pyrazolo[1,5-A]pyrimidines as tyrosine kinase inhibitors

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BACKGROUND OF THE INVENTION The present invention relates to compounds which inhibit, regulate and/or modulate tyrosine kinase signal transduction, compositions which contain these compounds, and methods of using them to treat tyrosine kinase-dependent diseases and conditions, such as angiogenesis,

atrophy/edema

Diagnostic method and system for detecting early age macular degeneration, maculopathies and cystoid macular edema post cataract surgery

Diagnostic method and system for detecting early age-related macular degeneration, maculopathies and cystoid macular edema post cataract surgery

Treatment of macular edema

Compositions and methods for treating macular edema

Norrin regulation of cellular production of junction proteins and use to treat retinal vasculature edema

Norrin regulation of cellular production of junction proteins and use to treat retinal vasculature edema

Methods and compositions for treatment of macular and retinal disease

Quinoline derivatives and their use as tyrosine kinase inhibitors

Quinoline derivatives and their use as tyrosine kinase inhibitors

Glucocorticoids attached to nitrate esters via an aromatic linker in position 21 and their use in ophthalmology

Glucocorticoids attached to nitrate esters via an aromatic linker in position 21 and their use in ophthalmology

Therapeutic treatment for VEGF related ocular diseases

Tyrosine kinase inhibitors

Polymorphs with tyrosine kinase activity

Substituted pyrazolo[1,5-A]pyrimidines as tyrosine kinase inhibitors

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