Patient who diagnostic of Breast cancer, Colorectal cancer, cancer of Ovary, and cancer of Endometrial are can recruit.

Breast Cancer

Colorectal Cancer

Cancer of Ovary

Cancer of Endometrium

Diagnosis and acceptance of breast cancer, colon rectal cancer, ovarian cancer, and endometrial cancer by the clinical Western medicine team.

Cases for patients diagnosed with breast cancer, colonrectal cancer, ovarian cancer and endometrial cancer

China Medical University Hospital

Immunoassay and Regulation of Traditional Chinese Medicine on Cancer Patients

The cytokines expression of immune cells in the blood by traditional Chinese medicine treatment in breast cancer, colon-rectal cancer, ovarian cancer, and endometrial cancer will be investigated.

Patients in the B group were given berberine hydrochloride tables 0.3g tid orally or tube feed daily, until the 14th day of the study. Other treatments include general support therapy, oxygen therapy, antiviral drugs, in combination with antibiotics and small doses of glucocorticoids if necessary, nutritional and organ function support.

Patients in the C group were given montmorilonite orally if they presence of diarrhea. The other treatments were the same as in B group.

Berberine

COVID-19

Patients in the intervention group received berberine daily, regardless of gastrointestinal symptoms.If the patient has a serious drug-related adverse event, the drug will be discontinued and the patient will be excluded from the study.

Patients in the control group were routinely not given special treatment.However, if the patient has diarrhea symptoms, montmorillonite powder should be given orally.

Montmorrillonite

Nanjing Drum Tower Hospital

The Effect of Berberine on Intestinal Function and Inflammatory Mediators in Severe Patients With Covid-19

Including diarrhea in times/day, Bristol Stool Scale (the minimum 1 and maximum 7, a higher scores mean a worse outcome) and whether patient has any one of gastrointestinal symptoms (nausea, vomiting, abdominal pain, abdominal distension or diarrhoea).

evaluate inflammatory response, blood sample collected at 6:00am

evaluate the severity of the disease(the minimum 0 and maximum 24, a higher scores mean a worse outcome)

We have other articles about covid-19 yet to be published

Chinese Medical Association

Schizophrenia

Therapeutics

Berberine 300mg（three times a day） plus any atypical antipsychotic drug

Any atypical antipsychotic drug as the basic treatment

atypical antipsychotic

The placebo were matched to Berberine in shape, smell and colour and capsules were sealed in identical bottles

placebo

Berberine Effects on Clinical Symptoms and Metabolic Disturbance in Patients With Schizophrenia

Berberine Effects on Clinical Symptoms and Metabolic Disturbance as an Adjunctive Therapy in Patients With Schizophrenia: a Randomized Double-blind Placebo-controlled Study

Positive and Negative Syndrome Scale（PANSS）has been used to assess symptom severity in schizophrenia.Of the items included in PANSS ,seven constitute a Positive scale,seven form a Negative scale and sixteen constitute a General Psychopathology scale.7-point rating instrument was conceived.A total Score is computed three subscales.Minimum scores is 30 and maximum scores is 210.The higher score are considered the psychiatric symptoms more serious.

The levels of FBG has been obtained at 3 point intervals: 0, 4, 8 weeks

The levels of Insulin has been obtained at 3 point intervals: 0, 4, 8 weeks

The levels of TC has been obtained at 3 point intervals: 0, 4, 8 weeks

The levels of TG has been obtained at 3 point intervals: 0, 4, 8 weeks

The levels of HDL-C has been obtained at 3 point intervals: 0, 4, 8 weeks

The levels of LDL-C has been obtained at 3 point intervals: 0, 4, 8 weeks

The levels of CRP has been obtained at 3 point intervals: 0, 4, 8 weeks

The levels of IL-1β has been obtained at 3 point intervals: 0, 4, 8 weeks

The levels of IL-6 has been obtained at 3 point intervals: 0, 4, 8 weeks

The levels of TNF-α has been obtained at 3 point intervals: 0, 4, 8 weeks

berberine/nekrozė

Immunoassay and Regulation of Traditional Chinese Medicine on Cancer Patients

The Effect of Berberine on Intestinal Function and Inflammatory Mediators in Severe Patients With Covid-19

Berberine Effects on Clinical Symptoms and Metabolic Disturbance in Patients With Schizophrenia

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