Lithuanian
Albanian
Arabic
Armenian
Azerbaijani
Belarusian
Bengali
Bosnian
Catalan
Czech
Danish
Deutsch
Dutch
English
Estonian
Finnish
Français
Greek
Haitian Creole
Hebrew
Hindi
Hungarian
Icelandic
Indonesian
Irish
Italian
Japanese
Korean
Latvian
Lithuanian
Macedonian
Mongolian
Norwegian
Persian
Polish
Portuguese
Romanian
Russian
Serbian
Slovak
Slovenian
Spanish
Swahili
Swedish
Turkish
Ukrainian
Vietnamese
Български
中文(简体)
中文(繁體)
calmodulin/sarkoma
Nuoroda įrašoma į mainų sritį
Puslapis 1 nuo 41 rezultatus
Phosphorylation of tyrosine residues of calmodulin in Rous sarcoma virus-transformed cells.
Straipsnius versti gali tik registruoti vartotojai
Prisijungti Registracija
Calmodulin, a wide-spread eukaryotic Ca2+-binding protein, was phosphorylated at its tyrosine residues in Rous sarcoma virus (RSV)-transformed chicken and rat cells but not in normal chicken embryo fibroblasts. In contrast, serine and threonine phosphorylation of calmodulin was found to occur in
Antitumor effect of a calmodulin antagonist on the growth of solid sarcoma-180.
Straipsnius versti gali tik registruoti vartotojai
Prisijungti Registracija
A calmodulin antagonist, N-(6-aminohexyl)-5-chloro-1-naphthalenesulfonamide (W-7), proved to have antitumor activity against solid Sarcoma-180. In particular, intraperitoneal injection of W-7 strongly inhibited the growth of solid Sarcoma-180 in mice given a daily dose, 10 mg/kg for 10 consecutive
Reversal of drug resistance in sarcoma-45 by the new calmodulin antagonist--trihydrochloride of [1,2,5-trimethyl-4-phenyl-4-beta-[N-(beta-ethylamino)-N-4'-methoxybe nzy l]-ethylamino] piperidine (AR-2).
Straipsnius versti gali tik registruoti vartotojai
Prisijungti Registracija
The anti-drug resistance effect of three derivatives (AR-1, AR-2 and AR-3) of [1,2,5-trimethyl-4-phenyl-4-beta-(N,N-disubstituted-ethylamino)] piperidines, that were evaluated as calcium and calmodulin antagonists, was studied on doxorubicin (ADM) and vincristine (VCR) resistant Sarcoma-45
A calmodulin-dependent protein kinase in Rous sarcoma virus-transformed rat cells and normal liver.
Straipsnius versti gali tik registruoti vartotojai
Prisijungti Registracija
A calmodulin-dependent protein kinase has been purified extensively from a Rous sarcoma virus-transformed rat cell line (RR1022) and from normal rat liver. The calmodulin-dependent protein kinase activity was manifested by in vitro phosphorylation of a single Mr 57 000 endogenous phosphoprotein
[Calmodulin in osteogenic sarcoma].
Straipsnius versti gali tik registruoti vartotojai
Prisijungti Registracija
The activating role of phospho-(Tyr)-calmodulin on the epidermal growth factor receptor.
Straipsnius versti gali tik registruoti vartotojai
Prisijungti Registracija
The activity of calmodulin (CaM) is modulated not only by oscillations in the cytosolic concentration of free Ca(2+), but also by its phosphorylation status. In the present study, the role of tyrosine-phosphorylated CaM [P-(Tyr)-CaM] on the regulation of the epidermal growth factor receptor (EGFR)
[Hormones and auto-paracrine tumor growth regulators in osteogenic sarcoma].
Straipsnius versti gali tik registruoti vartotojai
Prisijungti Registracija
The paper analyzes the data of long-term studies made in the N. N. Blokhin Cancer Research Center, Russian Academy of Medical Sciences. The study dealt with androgen exchange, the baseline levels of serum sexual steroid hormones and their receptors in the tumor, the blood concentrations of the
Purification of the Rous sarcoma virus src kinase by casein-agarose and tyrosine-agarose affinity chromatography.
Straipsnius versti gali tik registruoti vartotojai
Prisijungti Registracija
A simple and effective purification method for the src kinase, the transforming gene product of Rous sarcoma virus, has been developed by using affinity chromatography on casein-agarose and tyrosine-agarose columns. NaDodSO4/polyacrylamide gel electrophoresis and silver staining analysis showed that
Disordered binding regions of Ewing's sarcoma fusion proteins.
Straipsnius versti gali tik registruoti vartotojai
Prisijungti Registracija
A relationship was found between the Amino acid (AA) composition, Intrinsic Protein Disorder (IPD) and Protein Binding Regions (PBRs) of the functional regions of Ewing's sarcoma protein (EWS) and oncogenic EWS fusion proteins (EFPs). EWS has high IPD and 64% predicted Disordered Binding Regions
Biosynthesis of calmodulin in normal and virus-transformed chicken embryo fibroblasts.
Straipsnius versti gali tik registruoti vartotojai
Prisijungti Registracija
We report here that the higher levels of calmodulin in transformed chicken embryo fibroblasts are due to an increase in the rate of synthesis of calmodulin that results from an increased amount of calmodulin-specific mRNA in transformed cells. Transformation of several types of eucaryotic cells by
The role of calmodulin in the proliferation of transformed and phenotypically normal tsASV-infected rat cells.
Straipsnius versti gali tik registruoti vartotojai
Prisijungti Registracija
NRK cells infected with a temperature-sensitive, transformation-defective mutant of avian sarcoma virus (ASV), tsLA23, behaved as if nontransformed at a nonpermissive 40 degrees C and were rendered quiescent by serum deprivation. These serum-deprived cells were stimulated to start entering S phase
Regulation of intracellular levels of calmodulin and tubulin in normal and transformed cells.
Straipsnius versti gali tik registruoti vartotojai
Prisijungti Registracija
Transformation of mammalian tissue culture cells by oncogenic viruses results in a 2-fold increase in the intracellular concentration of calmodulin quantitated by radioimmunoassay. The two pairs of companion cell lines used in this study were the Swiss mouse 3T3/simian virus 40-transformed 3T3 cells
Down-regulation of a calmodulin-related gene during transformation of human mammary epithelial cells.
Straipsnius versti gali tik registruoti vartotojai
Prisijungti Registracija
A human cDNA library obtained from cultured normal mammary epithelial cells (HMECs) was searched by subtractive hybridization for genes whose decrease in expression might be relevant to epithelial transformation. One clone identified by this procedure corresponded to a 1.4-kilobase mRNA, designated
Calmodulin and Ca2+ in normal and transformed cells.
Straipsnius versti gali tik registruoti vartotojai
Prisijungti Registracija
Numerous lines of evidence implicate calcium and calmodulin (CaM) as regulators of cell growth and functional differentiation. In light of this evidence, several studies of the possible involvement of the CaM system in cellular transformation by RNA and DNA tumor viruses have been carried out. This
Calcium/calmodulin regulation of the rat prolactin gene is conferred by the proximal enhancer region.
Straipsnius versti gali tik registruoti vartotojai
Prisijungti Registracija
The effects of the calcium/calmodulin signaling system on expression of the rat PRL gene were studied in rat pituitary GH3 cells using two specific naphthalene sulfonamide calmodulin (CaM) antagonist drugs, W7 and a more potent and more highly specific iodo-derivative, 5-iodo-1-C8. PRL (but not GH)
Išsamiausia vaistinių žolelių duomenų bazė, paremta mokslu
- Dirba 55 kalbomis
- Žolelių gydymas, paremtas mokslu
- Vaistažolių atpažinimas pagal vaizdą
- Interaktyvus GPS žemėlapis - pažymėkite vaistažoles vietoje (netrukus)
- Skaitykite mokslines publikacijas, susijusias su jūsų paieška
- Ieškokite vaistinių žolelių pagal jų poveikį
- Susitvarkykite savo interesus ir sekite naujienas, klinikinius tyrimus ir patentus
Įveskite simptomą ar ligą ir perskaitykite apie žoleles, kurios gali padėti, įveskite žolę ir pamatykite ligas bei simptomus, nuo kurių ji naudojama.
* Visa informacija pagrįsta paskelbtais moksliniais tyrimais
