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4 rezultatus
Carvacrol induces the apoptosis of pulmonary artery smooth muscle cells under hypoxia.
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Prisijungti Registracija
The abnormal apoptosis of pulmonary artery smooth muscle cells (PASMCs) is an important pathophysiological process in pulmonary vascular remodeling and pulmonary arterial hypertension (PAH). Carvacrol, an essential oil compound from oregano and thyme, has displayed antimicrobial, antitumor, and
The transient receptor potential vanilloid-3 regulates hypoxia-mediated pulmonary artery smooth muscle cells proliferation via PI3K/AKT signaling pathway.
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UNASSIGNED
Transient receptor potential vanilloid 3 (TRPV3) is a member of the TRP channels family of Ca2+ -permeant cation channels. In this study, we aim to investigate the role of TRPV3 in pulmonary vascular remodeling and PASMCs proliferation under hypoxia.
METHODS
The expression of TRPV3 was
Carvacrol alleviates ischemia reperfusion injury by regulating the PI3K-Akt pathway in rats.
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Prisijungti Registracija
BACKGROUND
Liver ischemia reperfusion (I/R) injury is a common pathophysiological process in many clinical settings. Carvacrol, a food additive commonly used in essential oils, has displayed antimicrobials, antitumor and antidepressant-like activities. In the present study, we investigated the
TRPM7 inhibitor carvacrol protects brain from neonatal hypoxic-ischemic injury.
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Prisijungti Registracija
BACKGROUND
Our previous study found that suppression of TRPM7 reduced neuronal death in adult rat ischemic brain injury. It was reported that carvacrol blocked TRPM7 and attenuated brain injury in an adult rat MCAO model. The effects of carvacrol on neonatal stroke remain unknown. This study
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