4 rezultatus
Patients diagnosed with breast cancer can sometimes wait up to 6 weeks for their surgery. The wait leading up to surgery is a potentially long and anxious time. Since no treatment is happening during this period anyway, this study will allow patients to receive CQ during this waiting period. This
Patients Patients with LC, CRC and BC with good performance status and with tumor tissue available, at failure of conventional therapies or without possibility to be treated with therapy of proven efficacy, will be included in the study. Initial patient characterization will include detailed
The purpose of this study is to determine the anti-tumor activity of the combination of Chloroquine combined with a Taxane or Taxane-like chemo agents(Paclitaxel, Docetaxel, Abraxane, Ixabepilone).
The laboratories have developed robust preclinical models utilizing both in vitro systems such as the
In response to various stresses, cells can launch a process of "self-eating", termed autophagy. Thereby, components of the cell are catabolically digested via specific lysosomes called autophagosomes, to provide the cell with energy and other necessary factors to serve as a temporary survival