cluster headache/fatigue

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Sumatriptan. A reappraisal of its pharmacology and therapeutic efficacy in the acute treatment of migraine and cluster headache.

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Sumatriptan is a potent and selective agonist at a vascular serotonin1 (5-hydroxytryptamine1; 5-HT1) receptor subtype (similar to 5-HT1D) and is used in acute treatment of migraine and cluster headache. Following administration of sumatriptan 100mg orally, relief of migraine headache (at 2 hours)

Migraine and cluster headache--their management with sumatriptan: a critical review of the current clinical experience.

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Sumatriptan is a potent and selective agonist at the vascular 5HT1 receptor which mediates constriction of certain large cranial blood vessels and/or inhibits the release of vasoactive neuropeptides from perivascular trigeminal axons in the dura mater following activation of the trigeminovascular

Clomiphene citrate as a preventive treatment for intractable chronic cluster headache: a second reported case with long-term follow-up.

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OBJECTIVE To describe a second case of treatment refractory chronic cluster headache responsive to clomiphene citrate and with long-term follow-up. METHODS Case report with 7-year evaluation. METHODS A 63-year-old man with a 17-year history of chronic cluster headache preceded to have significant

Symptoms and diseases and smoking habits in female episodic cluster headache and migraine patients.

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Twenty-seven episodic female cluster headache patients were compared to 27 age-matched female migraine patients with regard to occurrence of symptoms and diseases other than headache, and also with regard to tobacco consumption. Some symptoms and diseases were found to occur significantly or almost

Magnesium depletion with hypo- or hyper- function of the biological clock may be involved in chronopathological forms of asthma.

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Asthma is a chronic, inflammatory disorder of the airways leading to airflow limitation. Its worldwide rise, mainly in developed countries, is a matter of concern. Nocturnal asthma (NA) frequently occurs and concerns two thirds of asthmatics. But, it remains controversial whether NA is a distinct

Chronopathological forms of magnesium depletion with hypofunction or with hyperfunction of the biological clock.

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The main mechanisms of the chronopathological forms of magnesium depletion associate a low Mg intake with various dysregulating biorhythms. The differentiation between forms with hyperfunction and forms with hypofunction of the biological clock is seminal and the main marker is the production of

Sleep, chronic pain, and opioid risk for apnea.

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Pain is an unwelcome sleep partner. Pain tends to erode sleep quality and alter the sleep restorative process in vulnerable patients. It can contribute to next-day sleepiness and fatigue, affecting cognitive function. Chronic pain and the use of opioid medications can also complicate the management

Sleep and pain.

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Noxious stimuli and painful disorders interfere with sleep, but disturbances in sleep also contribute to the experience of pain.Chronic paroxysmal hemicrania and possibly cluster headaches are related to REM sleep. Whereas headache is associated with snoring and sleep apnea, morning headaches are

Sumatriptan. An updated review of its use in migraine.

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Sumatriptan is a selective agonist at serotonin 5-HT1-like receptors, including 5-HT1B/1D subtypes. It is an effective treatment for acute migraine attacks and the injectable form has also shown efficacy in the treatment of cluster headaches. In placebo-controlled clinical trials, sumatriptan,

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