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7 rezultatus
Cannabinoid receptor modulators
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CROSS-REFERENCE TO RELATED APPLICATIONS
This application is a National Stage Application under 35 U.S.C. .sctn.371 of International Application No. PCT/US2010/002360, filed Aug. 27, 2010, which claims priority under 35 U.S.C. .sctn.119(e) to U.S. Provisional Application Nos. 61/275,506, filed Aug.
Cannabinoid receptor modulators
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FIELD OF THE INVENTION
The present invention relates to certain compounds of Formula Ia and pharmaceutical compositions thereof that modulate the activity of the cannabinoid CB.sub.2 receptor. The present invention further relates to certain compounds of Formula Ia and pharmaceutical compositions
Compounds with a combination of cannabinoid-CB.sub.1 antagonism and acetylcholinesterase inhibition
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This invention relates to the fields of pharmaceutical and organic chemistry, and provides compounds with a combination of cannabinoid-CB.sub.1 antagonism and cholinesterase inhibition, intermediates for synthesizing these compounds, formulations comprising these compounds, methods for preparing
Crystalline forms and processes for the preparation of cannabinoid receptor modulators
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FIELD OF THE INVENTION
The present invention relates to crystalline forms of (1aS,5aS)-2-(4-oxy-pyrazin-2-yl)-1a,2,5,5a-tetrahydro-1H-2,3-diaza-cyclop- ropa[a]pentalene-4-carboxylic acid ((S)-1-hydroxymethyl-2,2-dimethyl-propyl)-amide (Compound 1) and pharmaceutical compositions thereof that
Crystalline forms and processes for the preparation of cannabinoid receptor modulators
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FIELD OF THE INVENTION
The present invention relates to crystalline forms of (1aS,5aS)-2-(4-oxy-pyrazin-2-yl)-1a,2,5,5a-tetrahydro-1H-2,3-diaza-cyclop- ropa[a]pentalene-4-carboxylic acid ((S)-1-hydroxymethyl-2,2-dimethyl-propyl)-amide (Compound 1) and pharmaceutical compositions thereof that
Vasodilator cannabinoid analogs
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BACKGROUND OF THE INVENTION
FIELD OF THE INVENTION
The present invention relates to the discovery of novel ligands specific for a receptor from the cannabinoid (CB) receptor family. The invention discloses the discovery of novel ligands specific to this receptor that act as antagonists to the
Cannabinoids as antioxidants and neuroprotectants
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FIELD OF THE INVENTION
The present invention concerns pharmaceutical compounds and compositions that are useful as tissue protectants, such as neuroprotectants and cardioprotectants. The compounds and compositions may be used, for example, in the treatment of acute ischemic neurological insults or
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