ethyl acetate/sarkoma

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Disseminated cutaneous Kaposi sarcoma in a patient receiving triptolide/tripdiolide for rheumatoid arthritis.

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BACKGROUND To date, Kaposi sarcoma has not been mentioned among the adverse effects of triptolide/tripdiolide, ethyl acetate extracts or polyglycosides of the Chinese herbal remedy Tripterygium wilfordii Hook F. METHODS A patient was diagnosed with rheumatoid arthritis at the age of 29 years. She

Comparative Antitumor Activity of Different Solvent Fractions from an Auricularia auricula-judae Ethanol Extract in P388D1 and Sarcoma 180 Cells.

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The objective of this study was to evaluate and compare the antitumor activity of different solvent fractions (ethanol, dichloromethane, ethyl acetate, butanol and water) of the Auricularia auricula-judae 70% ethanol extract on the P388D1 macrophage and sarcoma 180 cells. A dose-dependent antitumor

Ethyl acetate extract from marine sponge Hyattella cribriformis exhibit potent anticancer activity by promoting tubulin polymerization as evidenced mitotic arrest and induction of apoptosis.

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BACKGROUND Marine sponges are important sources of bioactive compounds. OBJECTIVE This study investigated the anticancer properties of Hyattella cribriformis ethyl acetate (EA) fraction in various cancer and normal cell lines. METHODS anticancer assay was carried out in 15 cell lines to evaluate the

Rutamarin, an Active Constituent from Ruta angustifolia Pers., Induced Apoptotic Cell Death in the HT29 Colon Adenocarcinoma Cell Line.

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BACKGROUND Ruta angustifolia Pers. is a perennial herb that is cultivated worldwide, including Southeast Asia, for the treatment of various diseases as traditional medicine. OBJECTIVE The purpose of the study was to identify an active principle of R. angustifolia and to investigate its effect on the

Activation by caecal reduction of the azo dye D & C red no. 9 to a bacterial mutagen.

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D & C Red No. 9 is a monoazo dye used for manufacturing printing inks, rubber and plastics, and as an additive in cosmetics and drugs. In an NTP carcinogenicity study in rats and mice it induced splenic sarcomas and liver nodules in male rats; no chemical-related tumours were induced in mice. On the

Anti-proliferative effect of leaf extracts of Eucalyptus citriodora against human cancer cells in vitro and in vivo.

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Six different extracts from Eucalyptus citriodora leaves were investigated for their anticancer effect. Extracts were prepared using a range of polar and non-polar solvents to leach out maximum active components. Phytochemical analysis of the extracts revealed the presence of anthraquinones, cardiac

Cytotoxic effect of buckwheat (Fagopyrum esculentum Moench) hull against cancer cells.

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Buckwheat (Fagopyrum esculentum Moench) hull was extracted with 70% ethanol and then further fractionated with n-hexane, chloroform, ethyl acetate, and water stepwise. In the in vitro test (SRB assay), hexane and ethyl acetate fractions showed higher inhibition effects against MCF-7 cells than other

In vitro and in vivo antiproliferative activity of Calotropis procera stem extracts.

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The cytotoxic potential of stem organic extracts from Calotropis procera (Asclepiadaceae) was firstly evaluated against cancer cell lines by MTT assay. Subsequently, samples considered cytotoxic were tested for antimitotic activity on sea urchin egg development and for in vivo antiproliferative

Screening antitumor bioactive fraction from Sauromatum giganteum (Engl.) Cusimano & Hett and sensitive cell lines with the serum pharmacology method and identification by UPLC-TOF-MS.

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Sauromatum giganteum (Engl.) Cusimano & Hett Tuber are used in Chinese folklore medicine for treatment of neoplasms. However, the claim has not been scientifically validated. The aim of the study is to screen the antitumor bioactive fraction of Sauromatum giganteum (Engl.) Cusimano & Hett

Gilvocarcins, new antitumor antibiotics. 1. Taxonomy, fermentation, isolation and biological activities.

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Gilvocarcin V and gilvocarcin M, a group of antitumor antibiotics with a novel skeleton, were discovered in culture broths of Actinomycete DO-38. The producing organism, subsequently determined to be a new species and named Streptomyces gilvotanareus (NRRL 11382). Gilvocarcin V and M were isolated

Antitumor activity of fermented noni exudates and its fractions.

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Noni has been extensively used in folk medicine by Polynesians for over 2000 year. Recent studies have shown that noni has a wide spectrum of therapeutic activities including inhibition of angiogenesis, anti-inflammatory effects and anti-cancer activities. Intraperitoneal (i.p.) injection of

Anti-inflammatory and anti-tumour effects of Abies georgei extracts.

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Chloroform (AGC), ethyl acetate (AGE) and n-butanol (AGB) extracts of Abies georgei were investigated for anti-tumour and anti-inflammatory activities in-vitro and in-vivo. AGC exhibited potent antiproliferative effects against A549, LOVO, QGY-7703 and 6T-CEM tumour cells, with EC50 values of 77.5,

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