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field/antidepresantas
Nuoroda įrašoma į mainų sritį
Puslapis 1 nuo 2490 rezultatus
Antidepressant drugs and heart electrical field.
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Some antidepressant drugs, especially tricyclic ones--(TCA), have cardiovascular side effects. To compare the effects of antidepressant drugs, the electrocardiogram (ECG), vectorcardiogram (VCG), and body surface maps (BSM) were recorded in psychiatric patients without cardiovascular diseases
An open field study of antidepressant drugs.
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Eight psychotropic drugs, mainly acting on the catecholaminergic systems, were investigated in an open field setting. All drugs but one showed a significant reduction in overall activity over time. Only piribedil at 32 mg/kg showed an increase, while 2 mg/kg showed a decrease over time. Amineptine
Overview of the field.
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Clinical descriptions of depression date back to antiquity. Scientific investigations of mood disorders started only 150 years ago. An historical overview of depression leads into today's knowledge that depressive disorders are common, serious, and sometimes life-threatening and that their effects
[Current developments in the field of antidepressive agents].
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Field-realistic antidepressant exposure disrupts group foraging dynamics in mosquitofish.
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Psychoactive pollutants, such as antidepressants, are increasingly detected in the environment. Mounting evidence suggests that such pollutants can disrupt the behaviour of non-target species. Despite this, few studies have considered how the response of exposed organisms might be mediated by social
Commentary [the mood in the field of antidepressant drug discovery].
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Effects of antidepressant agents on open field behaviour in rats.
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Repeated administration of antidepressants decreases field potentials in rat frontal cortex.
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The effects of repeated administration of a tricyclic antidepressant, imipramine, and a selective serotonin reuptake blocker, citalopram, for 14 days (10 mg/kg p.o., twice daily), were studied ex vivo in rat frontal cortex slices prepared 48 h after last dose of the drug. Treatment with both
Developments in the field of antidepressants, where do we go now?
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Major depression is a severe psychiatric syndrome with very high prevalence and socio-economic impact. Its pathophysiology is poorly known, yet several neurotransmitter systems and brain areas have been implicated. Selective serotonin (5-hydroxytryptamine, 5-HT) reuptake inhibitors (SSRI) and
Biomarkers predicting antidepressant treatment response: how can we advance the field?
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Major depression, affecting an estimated 350 million people worldwide, poses a serious social and economic threat to modern societies. There are currently two major problems calling for innovative research approaches, namely, the absence of biomarkers predicting antidepressant response and the lack
Plasma levels of dosulepine and heart electric field.
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Antidepressants, particularly tricyclic (TCA) antidepressants, may have cardiotoxic effects, such as cardiac arrhythmias, especially in patients with cardiovascular diseases. For most of TCA, no exact correlation between dosage, plasma levels and changes of ECG parameters of standard ECG has been
Antidepressant-like effects of cranial stimulation within a low-energy magnetic field in rats.
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BACKGROUND
Evidence suggests that a novel type of magnetic resonance imaging (MRI) scan called echo planar magnetic resonance spectroscopic imaging (EP-MRSI) has mood-elevating actions in humans during the depressive phases of bipolar disorder. We examined whether a low-energy component of EP-MRSI
Frequency-dependent block of field potentials in the rat hippocampal slice caused by tricyclic antidepressants.
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The effect of the tricyclic antidepressants imipramine and desipramine were studied on field potentials in the rat hippocampal slice. The electrically evoked stratum radiatum nerve volley, excitatory postsynaptic potential (e.p.s.p.) and pyramidal cell layer population spike (PS) were recorded in
Electric field causes volumetric changes in the human brain.
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Recent longitudinal neuroimaging studies in patients with electroconvulsive therapy (ECT) suggest local effects of electric stimulation (lateralized) occur in tandem with global seizure activity (generalized). We used electric field (EF) modeling in 151 ECT treated patients with depression to
Comparative molecular field analysis using selectivity fields reveals residues in the third transmembrane helix of the serotonin transporter associated with substrate and antagonist recognition.
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The human serotonin transporter (hSERT) regulates the spatial and temporal actions of serotonin (5-HT) neurotransmission by removing 5-HT from the synapse. Previous studies have identified residues in the third transmembrane helix (TMH) that may be important for substrate translocation or antagonist
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