gallstones/phosphatase

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Isolated hyperphosphatasaemia in hepatobiliary disease. Correlation between serum alkaline phosphatase and bilirubin in 222 patients with gallstone disease and 61 patients with pancreatic cancer (44 with hepatic metastasis).

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The Clinical Relevance of the IBD-Associated Variation within the Risk Gene Locus Encoding Protein Tyrosine Phosphatase Non-Receptor Type 2 in Patients of the Swiss IBD Cohort.

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OBJECTIVE The single nucleotide polymorphism (SNP) rs1893217 within the gene locus encoding protein tyrosine phosphatase non-receptor type 2 (PTPN2) results in a dysfunctional PTPN2 protein is associated with Crohn's disease (CD) and exists in perfect linkage disequilibrium with the CD- and

Umbilical sinus tract with gallstone extrusion after laparoscopic cholecystectomy.

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There are an increasing number of reports concerning complications after laparoscopic cholecystectomy. We report a case of persistent elevation of serum alkaline phosphatase and spillage of several gallstones through an abdominocutaneous sinus tract to the umbilicus with spontaneous resolution.

[Isoenzyme profile of alkaline phosphatase in patients with pancreatitis].

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In patients with pancreatitis an increase of the total amount of alkaline phosphatase (ALP; EC 3.1.3.1) and the appearance of its macro isoenzyme which parallels the decrease of bone isoenzyme was found. This isoenzymatic profile suggests that the increase of ALP in pancreatitis is due to the

Gallstone pancreatitis: a prospective study on the incidence of cholangitis and clinical predictors of retained common bile duct stones.

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OBJECTIVE The aim of this study was to define the incidence of cholangitis in gallstone pancreatitis, in the absence of cholangitis, to identify the clinical predictors of persistent common bile duct (CBD) stones at endoscopic retrograde cholangiography (ERCP) or at intraoperative cholangiography

Cost-effectiveness analysis of laparoscopic versus minilaparotomy cholecystectomy for gallstone disease. A randomized trial.

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OBJECTIVE To evaluate the total cost of minilaparotomy cholecystectomy (MC) and laparoscopic cholecystectomy (LC) and perform a cost-effectiveness (CE) analysis. METHODS One hundred adult subjects with painful gallstone disease were randomized: 59 cases for LC and 41 cases for MC. Patients with

Possible role of a defect in hepatic bilirubin glucuronidation in the initiation of cholesterol gallstones.

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Abnormally low activity of hepatic bilirubin UDP-glucuronosyltransferase was found in 25% of 81 unselected patients with gallstones, as compared with only 3% in 35 controls. At the time of cholecystectomy, the stones were taken for analysis in 48 of 81 patients, and a bile sample was obtained in 42

[Survey on Clonorchis sinensis infection and bile component of gallstone patients from the Pearl River Delta region in Guangdong Province].

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OBJECTIVE To evaluate the prevalence of Clonorchis sinensis and bile components of gallstone patients from the Pearl River Delta region in Guangdong Province. METHODS From June 2011 to November 2012, 406 gallstone patients from the Pearl River Delta region in Guangdong Province were enrolled in the

Predictability of clinicobiochemical scoring systems for early identification of severe gallstone-associated pancreatitis.

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Early identification of severe gallstone-associated acute pancreatitis (GAAP) is a prerequisite for treatment with urgent endoscopic sphincterotomy. This study assesses the value of two clinicobiochemical scoring systems to this end. Over the 7-year period from 1983 to 1989, 100 consecutive patients

Obesity and risk of gallstone development on a 1200 kcal/d (5025 Kj/d) regular food diet.

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OBJECTIVE Previous studies report a greatly increased risk of gallstone formation in obese persons during periods of caloric restriction on very low calorie formula diets. The aim of the present study was to assess the risk of gallstone development in moderately obese patients losing weight on a

[Posthepatic obstructive jaundice caused by primary extragonadal germ-cell tumor in a patient with glucose-6-phosphatase dehydrogenase deficiency].

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METHODS In patients with glucose-6-phosphatase dehydrogenase (G6PD) deficiency (favism) jaundice is usually caused by hemolysis due to stress, infection or following the application of drugs. We report on a 74-year-old Italian with known G6PD deficiency complaining of jaundice, weight loss and

Evidence for oxidative stress in the gall bladder mucosa of gall stone patients.

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BACKGROUND There is considerable evidence indicating that gall stone patients have altered gall bladder functions with respect to secretion and absorption and inflammation in mucus membrane when compared with gall stone free subjects. Increased levels of accelerated generation of reactive oxygen

Biochemical prediction of gallstones early in an attack of acute pancreatitis.

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Plasma concentrations of bilirubin, alkaline phosphatase (AP), and glutamic oxaloacetic transaminase (GOT) were measured during 122 attacks of acute pancreatitis in 114 patients, on the day of admission to hospital and 2 days after admission. Concentrations in 74 attacks associated with gallstones

Gallstones are associated with hidradenitis suppurativa: a population-based and hospital-based cross-sectional study from Denmark.

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BACKGROUND Hidradenitis suppurativa (HS) is a chronic inflammatory dermatological disease that was recently linked to the metabolic syndrome (MetS). MetS has been associated with gallstones, and nonalcoholic fatty liver has been suggested to be the hepatic expression of MetS. OBJECTIVE The objective

Persistent Increase in Serum Alkaline Phosphatase in a Patient with Monoclonal Gammopathy of Undefined Significance.

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We report the finding of alkaline phosphatase-immunoglobulin complex (macro-alkaline phosphatase (macro-ALP)) in a patient with persistently increased ALP activity. The identification of macro-ALP is important to rule out pathological causes of increased ALP activity and to avoid unnecessary

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