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heart failure/pykinimas

Nuoroda įrašoma į mainų sritį
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Benzisoxazole derivatives

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Prisijungti Registracija
BACKGROUND OF THE INVENTION This invention relates to benzisoxazole derivatives. These compounds have selective 5-HT.sub.4 receptor agonistic activity. The present invention also relates to a pharmaceutical composition, method of treatment and use, comprising the above derivatives for the treatment

Indazole derivatives

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Prisijungti Registracija
BACKGROUND OF THE INVENTION This invention relates to Indazole Derivatives. These compounds have selective 5-HT.sub.4 receptor agonistic activity. The present invention also relates to a pharmaceutical composition, method of treatment and use, comprising the above derivatives for the treatment of

Oxyindole derivatives

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Prisijungti Registracija
BACKGROUND OF THE INVENTION This invention relates to Oxyindole Derivatives. These compounds have selective 5-HT.sub.4 receptor agonistic activity. The present invention also relates to a pharmaceutical composition, method of treatment and use, comprising the above derivatives for the treatment of

Benzimidazolone compounds having 5-HT4 receptor agonistic activity

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Prisijungti Registracija
TECHNICAL FIELD This invention relates to novel benzimidazolone compounds. These compounds have selective 5-HT.sub.4 receptor agonistic activity. The present invention also relates to a pharmaceutical composition, a method of treatment and use comprising the above compounds for the treatment of

Use of a benzo[b]thiopene-2-carboximidamide derivative

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Prisijungti Registracija
The invention relates to the use of the benzo[b]-thiophene-2-carboximidamide derivative having formula I ##STR2## or pharmaceutically acceptable salts thereof, for the preparation of a medicament which is suitable for the treatment of heart failure, having high bioavailability without inducing

Benzimidazolone carboxylic acid derivatives

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Prisijungti Registracija
BACKGROUND OF THE INVENTION This invention relates to benzimidazolone carboxylic acid derivatives. These compounds have selective 5-HT.sub.4 receptor agonistic activity. The present invention also relates to a pharmaceutical composition, method of treatment and use, comprising the above derivatives

Benzimidazolone carboxylic acid derivatives

Straipsnius versti gali tik registruoti vartotojai
Prisijungti Registracija
BACKGROUND OF THE INVENTION This invention relates to benzimidazolone carboxylic acid derivatives. These compounds have selective 5-HT.sub.4 receptor agonistic activity. The present invention also relates to a pharmaceutical composition, method of treatment and use, comprising the above derivatives

Benzimidazolone carboxylic acid derivatives

Straipsnius versti gali tik registruoti vartotojai
Prisijungti Registracija
BACKGROUND OF THE INVENTION This invention relates to benzimidazolone carboxylic acid derivatives. These compounds have selective 5-HT.sub.4 receptor agonistic activity. The present invention also relates to a pharmaceutical composition, method of treatment and use, comprising the above derivatives

Aromatic amides of heterocyclic compounds and therapeutic compositions containing same

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Prisijungti Registracija
SUMMARY OF THE INVENTION According to our invention, in its broadest aspect, we provide a compound corresponding to the general formula (I): ##STR1## in which: R is a lower (C.sub.1 -C.sub.6) alkoxy or alkenoxy; R.sub.1 and R.sub.2, which may be the same or different, are selected from hydrogen,

Anti-psychotic (cycloalkenylalkylpiperidino) benzamides

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Prisijungti Registracija
SUMMARY OF THE INVENTION According to one aspect of our invention, we provide compounds of the general formula ##STR1## wherein R represents a lower alkoxy or lower alkenyloxy group; R.sup.1 and R.sup.2, which may be the same or different, each represent a hydrogen or halogen atom, or a
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