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Nuoroda įrašoma į mainų sritį
4 rezultatus
Search for new plant constituents with potential antiphlogistic and antiallergic activity.
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Prisijungti Registracija
Structure-activity relationships obtained from in vitro screening results obviously indicate that the highest inhibition effects on cyclooxygenase and 5-lipoxygenase are found amongst the class of phenolic compounds (flavonoids, polyphenols, coumestans, phenol carboxylic acids) and arachidonic acid
Pharmacokinetics and in-situ absorption studies of a new anti-allergic compound 73/602 in rats.
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Prisijungti Registracija
Compound 73/602 (AA) is a structural analogue of vasicinone, an alkaloid present in the leaves and roots of Adhatoda vasica (Acanthaceae). It possesses potent antiallergic activity in mice, rats and guinea pigs. The pK(a) of AA was determined to be 2.87+/-0. 19 by UV spectrophotometry. The
Herbal polysaccharides and cough reflex.
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Prisijungti Registracija
In the last decades plant substances have become a leading form of treatment of many respiratory symptoms, including cough. It has been shown that compounds purified form polysaccharides from Adhatoda vasica, Withania somnifera, and Glycyrrhiza glabra have various biological activities, such as
Differential modulation of IgE-dependent activation of human basophils by ambroxol and related secretolytic analogues.
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Prisijungti Registracija
Ambroxol is a widely used secretolytic agent originally developed from vasicine, a natural alkaloid found in Adhatoda vasica, extracts of which have been used to treat bronchitis, asthma, and rheumatism. We previously reported that ambroxol inhibits IgE-dependent mediator secretion from human mast
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