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Puslapis 1 nuo 16 rezultatus
Transient anoxia during Metarhizium robertsii growth increases conidial virulence to Tenebrio molitor.
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Little is known about the phenotypic effects of hypoxia and transient anoxia on the virulence of an entomopathogenic fungus. Conidia of Metarhizium robertsii were produced on: (1) potato dextrose agar medium (PDA) under normoxia; (2) PDA medium under continuous hypoxia; (3) PDA medium under
Genomic analysis and lactose transporter expression in Kluyveromyces marxianus CCT 7735.
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Kluyveromyces marxianus CCT 7735 has been used to produce ethanol, aromatic compounds, enzymes and heterologous proteins besides assimilates lactose as carbon source. Its genome has 10.7 Mb and encodes 4787 genes distributed in 8 nuclear chromosomes and one mitochondrial. Contrary to Kluyveromyces
Galectin-3 is modulated in pancreatic cancer cells under hypoxia and nutrient deprivation
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Pancreatic ductal adenocarcinoma is one of the most aggressive tumors with a microenvironment marked by hypoxia and starvation. Galectin-3 has been evaluated in solid tumors and seems to present both pro/anti-tumor effects. So, this study aims to characterize the expression of Galectin-3 from
Magnesium supplementation and perinatal hypoxia: outcome of a parallel group randomised trial in pregnancy.
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OBJECTIVE
To determine the effects of magnesium supplementation in pregnancy on the incidence of hypoxic-ischaemic encephalopathy (HIE).
METHODS
A randomised double-blind placebo-controlled study.
METHODS
A Midwife Obstetric Unit and its two referral hospitals in Cape Town, South Africa.
METHODS
A
The characterization of energized and partially de-energized (respiration-independent) beta-galactoside transport into Escherichia coli.
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Unidirectional fluxes of [14C]lactose by whole cells of Escherichia coli under highly energized and partially de-energized (in the presence of CN-) conditions are analyzed kinetically. When the cells are energized, the value for V influx is 0.45 +/- 0.01 mM internal concentration increment/s and Kt
[Clinical characteristics of Pneumocystis carinii pneumonia in children with systemic lupus erythematosus].
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OBJECTIVE
To identify the risk factors which will indicate the Pneumocystis carinii (Pc) infection in children with systemic lupus erythematosus (SLE) and investigate the clinical features and to elevate the level to find out the high-risk patients and make early diagnosis and treatment.
METHODS
The
Effects of altitude and two decongestant-antihistamine preparations on physiological functions and performance.
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Fourteen men were studied to determine the combined effects of two altitudes--388 and 3,810 m or 1,274 and 12,500 ft--and three preparations--lactose placebo, Compound A (Actified, and Compound B (Dristan). Subjects reported least attentiveness with A and greatest with placebo. Fatigue increased
Application of sildenafil for pulmonary hypertension in canines and foals.
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Pulmonary arterial hypertension is the most commonly recognized form of pulmonary hypertension in canines. Persistent pulmonary hypertension is a life-threatening condition in neonatal foals. Treatment of pulmonary hypertension in both canines and neonatal foals has focused on the correction of
Protective role of curcumin on renal ischemia reperfusion injury via attenuating the inflammatory mediators and Caspase-3.
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Renal ischemia/reperfusion (I/R) damage may arise due to nephron sparing surgery in patient with a solitary kidney of restricted renal parenchymas. Apoptosis, inflammation and oxidative stress play a significant role in the expansion of renal dysfunction following renal I/R. The aim of the current
Adhesion phenotype manifests an altered metabolic profile favoring glycolysis.
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To determine whether metabolic markers are differentially expressed in normal and adhesion fibroblasts with and without hypoxia exposure.
Prospective experimental study.
University research laboratory.
Fibroblasts established from normal peritoneum and adhesion tissues from the same patients.
In
Use of microfluidic technology to analyze gene expression during Staphylococcus aureus biofilm formation reveals distinct physiological niches.
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The Staphylococcus aureus cid and lrg operons play significant roles in the control of autolysis and accumulation of extracellular genomic DNA (eDNA) during biofilm development. Although the molecular mechanisms mediating this control are only beginning to be revealed, it is clear that cell death
Novel regulatory mutants of the phosphate regulon in Escherichia coli K-12.
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New pleiotropic mutants were isolated that express either the phoA, psiE or psiO promoter constitutively and simultaneously alter bacterial alkaline phosphatase regulation, carbon utilization or ultraviolet light sensitivity. To do this, Lac+ mutants were isolated from strains with the appropriate
[Interpretation of exhaled CO levels in studies on smoking].
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BACKGROUND
Exhaled carbon monoxide (ECO) concentration provides an easy, fast and non invasive means of assessing smoking status. However, some difficulties have to be considered when interpreting ECO levels.
BACKGROUND
CO is a non-specific biomarker of tobacco exposure. Its half-life is short (2-6
Partridgeberry polyphenols protect rat primary cortical neurons from oxygen-glucose deprivation-reperfusion-induced injury via suppression of inflammatory adipokines and regulation of HIF-1α and PPARγ.
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OBJECTIVE
The aim of this study was to investigate the neuroprotective ability of partridgeberry polyphenols in rat primary cortical neurons against oxygen-glucose deprivation/reperfusion (OGD/R) injury in vitro and explore the underlying therapeutic mechanism(s).
METHODS
The OGD/R injury was
Vitamin C supplementation influences the antioxidant response and nitric oxide handling of erythrocytes and lymphocytes to diving apnea.
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OBJECTIVE
We have investigated the influence of vitamin C diet supplementation on the antioxidant response and nitrite levels in lymphocytes and erythrocytes during diving apnea.
METHODS
Seven male professional apnea divers participated in a double blind crossover study. Divers were randomly
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