An anti-pathogen device may be useful as a wound dressing, an antibiotic sock, a mastitis cup, a tampon, or a window, door or bed cover. It comprises a carrier and a pathogen-binding component and a binding intermediate is attached to the carrier to facilitate binding of the pathogen-binding component to the carrier by forming a pathogen-binding construct with the pathogen-binding component. The pathogen binding construct may be lactoferrin, hololactoferrin, apolactoferrin, or asialolactoferrin. A carbohydrate binder binds the pathogen binding construct to the carrier.

VIRUSTATIC LIMITED

Virustatic Ltd.

Anti-pathogen device

A negatively-charged S. aureus antigen contains .beta.-hexosamine as a major carbohydrate component. S. aureus strains that carry the antigen account for nearly all of the clinically significant strains of S. aureus that are not Type 5 or Type 8 strains. The antigen can be used in combination with S. aureus Type 5 polysaccharide antigen and S. aureus Type 8 polysaccharide antigen to provide nearly 100% coverage of S. aureus infection. The antigen and antibodies to the antigen are useful in kits and assays for diagnosing S. aureus infection. A whole cell vaccine of cells that contain the antigen is particularly useful in the treatment of mastitis.

mastitis/carbohydrate

Anti-pathogen device

Staphylococcus aureus antigen-containing whole cell vaccine

Staphylococcus aureus antigen-containing whole cell vaccine

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