melanin/pykinimas

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Prochlorperazine interaction with melanin and melanocytes.

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Prochlorperazine is a phenothiazine-class antipsychotic drug usually used to treat nausea, vomiting and schizophrenia. Phenothiazine derivatives have been known to cause serious side effects, like extrapyramidal symptoms, but also skin disorders which mechanism has not been fully established. The

Amelanotic Meningeal Melanoma with Leptomeningeal Dissemination: A Case Report and Systematic Literature Review.

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BACKGROUND Meningeal melanoma is a rare tumor of the central nervous system, whose amelanotic variant is the so-called 'amelanotic meningeal melanoma (AMM)'. AMM does not produce melanin and therefore does not exhibit typical short-T1 and short-T2 signal on MRI, and thus can be easily misdiagnosed

Amelanotic malignant melanoma of the esophagus: report of two cases with immunohistochemical and molecular genetic study of KIT and PDGFRA.

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The author reports herein two cases of amelanotic malignant melanoma of the esophagus. Case 1 is an 87-year-old woman who was admitted to our hospital because of nausea and vomiting. Endoscopic examination revealed an ulcerated tumor of the distal esophagus, and a biopsy was taken. The biopsy showed

[Melanosis of choroid plexus papilloma of the lateral ventricle: a case report].

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A case of pigmented, well differentiated, choroid plexus papilloma is reported. A 45-year-old man came to our hospital complaining of attacks of vertigo and nausea. Skull X-ray films and CT scan demonstrated a calcified tumor in the left middle fossa. Tumor removal was done, and it was found that

Intraepithelial Melanoma in the Stomach After Treatment With Immune Checkpoint Blockade Therapy.

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Melanoma is the most common tumor to metastasize to the gastrointestinal tract, commonly affecting the small intestine, colon, and anorectum. Primary mucosal melanoma can arise in any gastrointestinal site, most frequently affecting anorectal mucosa. Melanoma involving the gastric mucosa,

Unusual tonsillar herniation in meningeal melanocytoma: a case report.

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Meningeal melanocytoma is a primary melanocytic neoplasm with certain MR and immunohistochemical characteristics worthy to note. In a 38-year-old man with a complaint of headache for a couple of years and recently added nausea, vomiting, diplopia, progressive visual blurring and hearing loss,

Primary colonic melanoma presenting as ileocecal intussusception: case report and literature review.

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Primary malignant melanoma originating in the colon is an extremely rare disease. Herein, we report a case of primary melanoma of the ascending colon. The patient was a 57-year-old male who was admitted to our hospital for persistent abdominal pain and episodes of bloody stool, nausea and vomiting.

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