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Adenosquamous carcinoma with cilium formation, mucin production and keratinization in the nasal cavity of a red fox (Vulpes vulpes schrencki).

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A diagnosis of adenosquamous carcinoma was made in an 11-year-old red fox. The animal showed emaciation and purulent nasal discharge. Necropsy revealed diffuse thickening of the nasal mucosa and tumours on the soft palate, and there was an oronasal fistula contiguous with the tumours. The nasal and

Salivary mucin 19 glycoproteins: innate immune functions in Streptococcus mutans-induced caries in mice and evidence for expression in human saliva.

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Saliva functions in innate immunity of the oral cavity, protecting against demineralization of teeth (i.e. dental caries), a highly prevalent infectious disease associated with Streptococcus mutans, a pathogen also linked to endocarditis and atheromatous plaques. Gel-forming mucins are a major

Polymer coated liposomes for use in the oral cavity - a study of the in vitro toxicity, effect on cell permeability and interaction with mucin.

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In this study we investigated the in vitro toxicity, impact on cell permeability and mucoadhesive potential of polymer-coated liposomes intended for use in the oral cavity. A TR146 cell line was used as a model. The overall aim was to end up with a selection of safe polymer coated liposomes with

Expression of salivary mucin bacterial aggregating activity: difference with caries.

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The low and high molecular weight mucin forms were isolated from saliva of individuals with different caries status and assessed for their bacterial aggregating potential towards S. mutans and S. sanguis. The high molecular weight mucin from both groups exhibited similar protein and carbohydrate

Differential expression of salivary mucin bacterial aggregating activity with caries status.

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1. The low and high mol. wt mucin forms were isolated from saliva of caries-resistant (CR) and caries-susceptible (CS) individuals, and assessed for their bacterial aggregating potential towards S. mutans and S. sanguis, the common cariogenic microorganisms encountered in the oral cavity. 2. The

Control of mucin molecular forms expression by salivary protease: differences with caries.

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1. A protease activity capable of degradation of the high mol. wt salivary mucus glycoprotein to a low mol. wt glycoprotein form was identified in human submandibular gland secretion. 2. The protease exhibited optimum activity at pH 7.0-7.4, and gave on SDS-PAGE under reducing conditions two major

Evaluation of salivary mucins in children with deciduous and mixed dentition: comparative analysis between high and low caries-risk groups.

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OBJECTIVE The aim of this study was to examine levels of salivary mucins in children with deciduous and mixed dentition and to determine correlations between salivary mucins and dental caries status in two dentition stages. METHODS Saliva samples were collected from preschool children with deciduous

Evaluation of secretory mucin concentration of patients with squamous cell carcinoma oral cavity.

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OBJECTIVE Secretory salivary mucins constitute a heterogenous group of glycoproteins, synthesized and secreted by submandibular, sublingual gland and small glands of oral mucosa. The most significant functions of mucins in case of oral cavity carcinoma are: participation in oral pellicle formation,

Role of salivary mucins in the protection of the oral cavity.

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Mucins are the principal organic constituents of mucus, the slimy visco-elastic material that coats all mucosal surfaces. Compelling evidence suggests that they play an integral role in non-immune protection of the oral cavity. Specific protective functions include: 1) protection against desiccation

[Association of the polymorphism of MUC7 gene encoding the low-molecular-weight mucin MG2 with susceptibility to caries].

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BACKGROUND The aim of this study was to search for an association of the polymorphism of MUC7 gene encoding the low-molecular-weight mucin MG2 with susceptibility to caries. METHODS The study enrolled 158 students (age 20-21 years) of the first and second year at the Faculty of Dentistry of the

Mucin levels in saliva of adolescents with dental caries.

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BACKGROUND Human saliva, a complex secretion that contains a mixture of inorganic and organic molecules, plays an essential role in the maintenance of oral health. Mucins are the major macromolecular component of the secretion and are considered the first line of defense for epithelial tissues. The

[Environmental factors in oral cavity effect on growing of Streptococcus sanguis and Streptococcus mutans-effect of Mucin]

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Our study use continues culture technique through adding mucin as the limiting element in chemically defined culture,medium in order to observe growing states of S.sanguis 34 and,S.mutants Ingbritt(c).The results as follows:S.sanguis 34 were able to grow as pure culture on mucin;S.mutans was unable

Identification of human salivary protease activity toward mucin: differences with caries.

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A protease activity directed toward high molecular weight salivary mucus glycoprotein was identified in the secretion of human submandibular salivary gland. The protease exhibited maximum activity at pH 7.0-7.4, and following ammonium sulfate fractionation yielded an active enzyme at 60% saturation

Mucin-bacterial interactions in the human oral cavity and digestive tract.

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Mucins are a family of heavily glycosylated proteins that are the major organic components of the mucus layer, the protective layer covering the epithelial cells in many human and animal organs, including the entire gastro-intestinal tract. Microbes that can associate with mucins benefit from this

[Mucin and dental caries].

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