6 rezultatus
For preterm infants, especially for very or extremely low birth weight infants, it's impossible to achieve total enteral feeding in short time. So, PN has played an important role to sustain normal life. But, it also has an adverse effect on liver namely parenteral nutrition-associated liver disease
Sphingolipids represent a major class of lipids that are structural and signaling molecules. Major bioactive sphingolipids include ceramide, dihydroceramide, sphingosine, sphingosine-1-phosphate and sphingomyelin.
Sphingoliplids are involved in development of various chronic metabolic diseases. Some
The following determinations will be made at baseline, mid-point, and end of each 20-week study period, as well as at one-year follow up:
General status, symptoms, and medication accounting. Participants will be asked to report changes in their health and medication use.
Disease Activity. The
Parenteral nutrition (PN) has been widely and successfully used in the pediatric population for more than 40 years, the most serious and significant life-threatening complication today continues to be parenteral nutrition-associated cholestasis(PNAC). Parenteral nutrition-associated cholestasis is
The following determinations will be made at baseline, mid-point, and end of each 20-week study period, as well as at one-year follow up:
General status, symptoms, and medication accounting. Participants will be asked to report changes in their health and medication use.
Disease Activity. The
NASH is a clinico-pathological entity characterized by the development of histological changes of inflammation and fibrosis in the liver that are nearly identical to those induced by excessive alcohol intake, but in the absence of alcohol abuse. Nonalcoholic steatohepatitis occurs commonly children