12 rezultatus
TECHNICAL FIELD
The present invention relates to the treatment of disorders using heme oxygenase-1 and heme degradation products.
BACKGROUND
Heme oxygenase-1 (HO-1) catalyzes the first step in the degradation of heme. HO-1 cleaves the .alpha.-meso carbon bridge of b-type heme molecules by oxidation
FIELD OF THE INVENTION
The present invention relates to hybrid fumarate-CO-releasing molecules capable of activating heme oxygenase-1 (HO-1) activity and HO-1 protein expression, their synthesis and their use in therapeutic applications, in particular their use in the treatment of inflammatory and
This invention relates to heterocyclic compounds and their preparation and to the use of such compounds of pharmaceutical formulations thereof in medicine in a mammal, including man, as e.g. anti-inflammatory or anti-allergic agents or as agents in the prevention of tissue rejection.
Accordingly,
FIELD OF THE INVENTION
This invention relates o cocoa extracts and compounds therefrom such as polyphenols preferably polyphenols enriched with procyanidins. This invention also relates to methods for preparing such extracts and compounds, as well as to uses for them; for instance, as antineoplastic
BACKGROUND OF THE INVENTION
1. Field of the Invention
This invention relates to the control of the inflammatory response, to pharmaceuticals that inhibit or decrease inflammation, to pharmaceuticals that promote, induce or increase inflammation and to treatment of disease states by inhibiting or
This invention relates to novel phenyl-pyrazolidine acetic acid derivatives possessing lipoxygenase/cyclooxygenase inhibitory activity, which are useful as anti-inflammatory and analgesic agents.
It is known that arachidonic acid (AA) is metabolized in mammals by two distinct pathways. The
BACKGROUND OF THE INVENTION
1. Field of the Invention
The present invention provides substituted fused imidazole derivatives that may be useful for control of an inflammatory response. In addition, the invention provides compounds, pharmaceutical compositions, and methods of use thereof for
BACKGROUND OF THE INVENTION
Field of the Invention
The present invention provides substituted fused imidazole derivatives that may be useful for control of an inflammatory response. In addition, the invention provides compounds, pharmaceutical compositions, and methods of use thereof for controlling
TECHNICAL FIELD
This invention describes a nutritional composition and method of use for prevention of Parkinson's disease, therefore relating to the fields of nutrition, pharmacology, neurology, pathophysiology, medicine and movement disorders.
DESCRIPTION OF THE RELATED ART
Parkinson's disease
This invention relates to formulations comprising heterocylic compounds and their preparation, to their use in medicine in a mammal, including man, e.g. as anti-inflammatory or anti-allergic agents or as agents in the prevention of tissue rejection, and to certain novel heterocylic compounds and
BACKGROUND OF THE INVENTION
I. Field of the Invention
The present invention provides novel tricyclic-bis-enone derivatives (TBEs), as well as the process for the preparation of such TBEs, for prevention and/or treatment of cancer, Alzheimer's disease, Parkinson's disease, multiple sclerosis,
BACKGROUND OF THE INVENTION
I. Field of the Invention
The present invention provides novel tricyclic-bis-enone derivatives (TBEs), as well as the process for the preparation of such TBEs, for prevention and/or treatment of cancer, Alzheimer's disease, Parkinson's disease, multiple sclerosis,