phaseolus vulgaris/seizures

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Afferents to the seizure-sensitive neurons in layer III of the medial entorhinal area: a tracing study in the rat.

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Neurons in layer III of the medial entorhinal area (MEA) in the rat are extremely vulnerable to local injections of amino-oxyacetic acid and to experimentally induced limbic seizures. A comparable specific pathology has been noted in surgical specimens from patients with temporal lobe epilepsy.

Projections from the lateral, basal and accessory basal nuclei of the amygdala to the perirhinal and postrhinal cortices in rat.

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The projections from the amygdaloid complex to the hippocampus and surrounding cortex have a critical role in the formation of memories for emotionally arousing stimuli and in the spread of epileptic seizures. The present study investigated the organization of amygdaloid projections to the

Interamygdaloid projections of the basal and accessory basal nuclei of the rat amygdaloid complex.

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Previous studies suggest that the left and right amygdalae are interconnected in rodents. The origin and topography of these connections have, however, remained obscure. In the present study, we investigated the interamygdaloid projections originating in the different divisions of the basal and

Intrinsic and efferent connections of the endopiriform nucleus in rat.

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The endopiriform nucleus is a large group of multipolar cells located deep to the piriform cortex. The function of this nucleus is unknown, but studies with animal models suggest that it plays an important role in temporal lobe epileptogenesis. To address questions concerning mechanisms of

The central piriform cortex: anatomical connections and anticonvulsant effect of GABA elevation in the kindling model.

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The piriform cortex (PC) is thought to be critically involved in the generation and propagation of forebrain (limbic type) seizures in the rat. The PC extends over a large area at the ventrolateral side of the rat brain with an anterior part highly sensitive for bicuculline-induced and a central

Synaptic and axonal remodeling of mossy fibers in the hilus and supragranular region of the dentate gyrus in kainate-treated rats.

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Seizures evoked by kainic acid and a variety of experimental methods induce sprouting of the mossy fiber pathway in the dentate gyrus. In this study, the morphological features and spatial distribution of sprouted mossy fiber axons in the dorsal dentate gyrus of kainate-treated rats were directly

[Longitudinal fiber systems in the hippocampal formation].

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Longitudinal fiber systems in the hippocampal formation play an important role in propagating information to the entire septotemporal extent of the hippocampus. Previously, we have elucidated the longitudinal axonal projections of CA3 pyramidal cells (Ishizuka et al., 1990, J Comp Neurol 295:

Projections from the amygdaloid complex to the piriform cortex: A PHA-L study in the rat.

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Projections from the amygdala to the piriform cortex are proposed to provide a pathway via which the emotional system can modulate the processing of olfactory information as well as mediate the spread of seizure activity in epilepsy. To understand the details of the distribution and topography of

Projections from the posterior cortical nucleus of the amygdala to the hippocampal formation and parahippocampal region in rat.

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The posterior cortical nucleus of the amygdala is involved in the processing of pheromonal information and presumably participates in ingestive, defensive, and reproductive behaviors as a part of the vomeronasal amygdala. Recent studies suggest that the posterior cortical nucleus might also modulate

Projections from the periamygdaloid cortex to the amygdaloid complex, the hippocampal formation, and the parahippocampal region: a PHA-L study in the rat.

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The periamygdaloid cortex, an amygdaloid region that processes olfactory information, projects to the hippocampal formation and parahippocampal region. To elucidate the topographic details of these projections, pathways were anterogradely traced using Phaseolus vulgaris leukoagglutinin (PHA-L) in 14

Efferent projections of the anterior perirhinal cortex in the rat.

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Because convulsive seizures develop very rapidly from kindling sites in the anterior perirhinal cortex, we studied perirhinal efferents by using the anterograde tracer Phaseolus vulgaris leucoagglutinin (PhAL). PhAL injections into the anterior perirhinal cortex labelled a prominent network of

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