phleum echinatum/astma

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Allergenic profile to Phleum pratense and immunological changes induced after grass allergen-specific immunotherapy.

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BACKGROUND The introduction of molecular diagnoses has provided evidence of the existence of several different allergenic profiles in grass-sensitised individuals, reflecting the large number of allergens involved. This methodology has become a potent tool for a correct diagnosis and for the

Intradermal Phleum pratense allergoid immunotherapy. Double-blind, randomised, placebo-controlled trial

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Background: In allergology, the intradermal approach is generally used to establish an etiological diagnosis, with limited experience in specific allergen immunotherapy. Objective:

Pattern of airway response to allergen extract of Phleum pratensis in asthmatic patients during and outside the pollen season.

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In order to evaluate the pattern of airway response to a specific bronchial provocative test (sBPT) with an extract of Phleum pratensis standardized in biological units (BU), we studied 27 patients with seasonal asthma due to grass pollen by means of allergologic evaluations, methacholine inhalation

Specific Immunotherapy in LAR: a randomized, double-blind placebo controlled trial with Phleum pratense subcutaneous allergen immunotherapy.

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BACKGROUND Allergen immunotherapy has been shown to be an effective treatment for local allergic rhinitis (LAR) to house dust mites. Studies with pollen allergen immunotherapy are limited to observational studies. The aim of this study was to evaluate the clinical efficacy and safety of Phleum

Component-resolved diagnosis for phleum allergy: the role of recombinants.

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BACKGROUND Conventional diagnostic tests (such as radioallergosorbent test [RAST] and skin prick test [SPT]) use native raw pollen allergen extracts to establish allergy. However, recombinant allergens may offer important advantages compared with their natural counterparts. OBJECTIVE This study

Diagnostic relevance of IgE sensitization profiles to eight recombinant Phleum pratense molecules.

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BACKGROUND Grass pollen-related seasonal allergic rhinoconjunctivitis (SARg) is clinically heterogeneous in severity, comorbidities, and response to treatment. The component-resolved diagnostics disclosed also a high heterogeneity at molecular level. Our study aimed at analyzing the characteristics

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