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photophobia/atrofija
Nuoroda įrašoma į mainų sritį
Puslapis 1 nuo 285 rezultatus
Light Sensitivity Within Areas of Geographic Atrophy Secondary to Age-Related Macular Degeneration.
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Bisretinoids mediate light sensitivity resulting in photoreceptor cell degeneration in mice lacking the receptor tyrosine kinase Mer.
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The receptor tyrosine kinase Mer is expressed by retinal pigment epithelial (RPE) cells and participates in photoreceptor outer-segment phagocytosis, a process enabling membrane renewal. Mutations in the gene encoding MERTK cause blinding retinitis pigmentosa in humans. Targeted Mertk disruption in
Photophobia, visual hallucinations, and REM sleep behavior disorder in progressive supranuclear palsy and corticobasal degeneration: a prospective study.
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Progressive supranuclear palsy (PSP) and corticobasal degeneration (CBD) have overlapping clinical features that can make clinical distinction between these two entities difficult. The present study compared the frequency of photophobia, visual hallucinations, and REM sleep behavior disorder (RBD)
Macular Sensitivity Measured With Microperimetry in Stargardt Disease in the Progression of Atrophy Secondary to Stargardt Disease (ProgStar) Study: Report No. 7.
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UNASSIGNED
New outcome measures for treatment trials for Stargardt disease type 1 (STGD1) and other macular diseases are needed. Microperimetry allows mapping of light sensitivity of the macula and provides topographic information on visual function beyond visual acuity.
UNASSIGNED
To measure and
Two cases of retinal degeneration with an unusual form of electroretinogram.
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An unusual form of retinal degeneration is reported in 15-year-old girl and 11-year-old girl with different pedigrees, which resembles the cases reported by Gouras and associates (1983). The subjective symptoms in these patients included decreased visual acuity, photophobia, anomalous color vision
[How good are the correlations between contrast sensitivity and differential light sensitivity in the visual field center in optic neuropathies?].
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Contrast sensitivity (CS) and differential light sensitivity (LUE) tend to deteriorate with increasing severity of the neuropathy. However, the correlation between the two psychophysical functions is low for the total number of optic neuropathies as well as for groups with different visual acuities.
An experimental study of the neurophysical mechanisms of photophobia induced by subarachnoid hemorrhage.
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BACKGROUND
Photophobia is defined as a painful psychosomatic discomfort triggered by intense light flow through the pupils to the brain, but the exact mechanism through which photophobia is induced by subarachnoid hemorrhage (SAH) is not well understood. In this study, we aimed to investigate
Local Abundance of Macular Xanthophyll Pigment Is Associated with Rod- and Cone-Mediated Vision in Aging and Age-Related Macular Degeneration
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Purpose: We assessed the association between the abundance of macular xanthophyll carotenoid pigment using dual-wavelength autofluorescence and multimodal vision testing including rod-mediated dark adaptation (RMDA), a measure of retinoid
Fatty acid transport protein 4 (FATP4) prevents light-induced degeneration of cone and rod photoreceptors by inhibiting RPE65 isomerase.
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Although rhodopsin is essential for sensing light for vision, it also mediates light-induced apoptosis of photoreceptors in mouse. RPE65, which catalyzes isomerization of all-trans retinyl fatty acid esters to 11-cis-retinol (11cROL) in the visual cycle, controls the rhodopsin regeneration rate and
A polymer optoelectronic interface restores light sensitivity in blind rat retinas.
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Interfacing organic electronics with biological substrates offers new possibilities for biotechnology due to the beneficial properties exhibited by organic conducting polymers. These polymers have been used for cellular interfaces in several fashions, including cellular scaffolds, neural probes,
Clinical study of a large family with autosomal dominant progressive cone degeneration.
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OBJECTIVE
Autosomal dominant cone degeneration is an uncommon disorder characterized by progressive photophobia, hemeralopia, decreased central vision, and dyschromatopsia. To better understand the variable expressivity of autosomal dominant cone degeneration, we studied a single, large
Cone and rod ERGs in degenerations of central retina.
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Sixty-four patients with retinal degenerations at the posterior pole were reviewed and their ERGs analysed. On the basis of symptoms, visual acuity, ophthalmoscopy and cone/rod ERG the patients were divided into five diagnostic groups: Stargardt's disease, fundus flavimaculatus, cone degeneration,
Pigmented paravenous retinochoroidal atrophy: a case report.
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BACKGROUND
Pigmented paravenous retinochoroidal atrophy (PPRCA) is an unusual retinal degeneration, and its performance on optical coherence tomography angiography (OCTA) is unclear. We report a Chinese female case of PPRCA and her OCTA features.
METHODS
A 66-year-old female patient was referred to
Dark adaptation in glaucomatous and nonglaucomatous optic nerve atrophy.
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Optic nerve damage is associated with impairment of psychophysical functions. We measured dark adaptation in 21 eyes of 14 normal subjects, 35 eyes of 19 patients with primary open-angle glaucoma, and 7 eyes of 4 patients with nonglaucomatous descending optic nerve atrophy. In the normal subjects
Clinical characteristics of recessive retinal degeneration due to mutations in the CDHR1 gene and a review of the literature.
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The clinical phenotype of patients presenting with autosomal recessive CDHR1-related retinopathy has not been well described.
This is a retrospective case series of patients presenting to a single institution. Clinical data, including age, visual acuity, dilated fundus exam, fundus photos, fundus
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