concentration of 1.3 billion of Lactobacillus acidophilus LAC-361 and Bifidobacterium longum BB-536. one pill twice a day. Each capsule contained maltodextrin and magnesium stearate as excipient

containing 10 billion Lactobacillus acidophilus LAC-361 and Bifidobacterium longum BB-536. One pill three times a day. Each capsule contained maltodextrin and magnesium stearate as excipient

Each capsule contained maltodextrin and magnesium stearate as excipient. One pill twice a day

Cancer

Diarrhea

Abdominal Pain

Quality of Life

placebo, standard dose 1.3 billion twice a day, high dose 10 billion three time a day

Bifilact®

placebo

CHU de Québec, radio-oncology departement

Impact of Probiotics BIFILACT® on Diarrhea in Patients Treated With Pelvic Radiation

Patients were asked to note in a daily logbook whether they experienced digestive problems such as daily bowel movements. Severity of the diarrhea was evaluated according to toxicity criteria of the WHO: grade 1 = increase of 2-3 stools per day compared to pre-treatment, grade 2 = increase of 4-6 bowel stools per day or nocturnal stools, grade 3 = increase of 7-9 stools per day or incontinence, grade 4 = increase of 10 or more stools, need for IV hydration. The Registered Dietitian assessed symptoms in logbook with the patient once a week.The duration of daily logbook was 4-9 weeks depending of the total dose of external radiotherapy

Registered Dietitian assessed respect of the preview protocol treatment each week (radiotherapy and chemotherapy) if not respected: diarrhea is it involved. For patients that received chemotherapy, a weekly blood profile was obtained and study pills were discontinued if neutrophil count became ≤1.5 X 10(9)/L.

Patients were asked to note, each day during the treatment,in a daily logbook intake of anti-diarrheal medication, laxatives, and antibiotics. The Registered Dietitian assessed symptoms noted with the patient each week.The duration of daily logbook was 4-9 weeks depending of the total dose of external radiotherapy

Abdominal pain was evaluated according to the NCI scale version 3.0: Grade 1 = mild pain, not interfering with function, grade 2 = moderate pain: pain or analgesics interfering with function, but not interfering with activity of daily living, grade 3 =: severe pain: pain or analgesics severely interfering with activity of daily living. The Registered Dietitian assessed information with the patient each week

Quality of life (EORTC-QLQ-C30) assessment was filled three times during the study: once at the outset, once at the end, and then again two weeks after the last radiotherapy treatment.

Registered Dietitian assessed each week if the patient had need hospitalization and if the diarrhea has involved

Mimi Demers

registered dietitian

CHU de Quebec-Universite Laval

weekly docetaxel (35mg/m&) plus prednisone 10mg a day associated with estramustine form day 1to 5 and 8 to 12

Hormone Resistant Prostate Cancer

Metastatic Prostate Cancer

35mg/m² on day 2 and 9 (21days in a cycle)

docetaxel

140mg caps x3 bid from day 1to 5 and day 8 to 12 of each cycle

estramustine

prednisone

St Pierre

Notre Dame et Reine Fabiola

RHMS louis caty

Clinique Saint Luc

CHR Warquignies

Az klina

Parc Léopold

Hôpitaux IRIS Sud

Cliniques Universitaires St luc

Sint Nilolaus

Clinique St Joseph

Notre Dame de Grâce

CH Jolimont Lobbes

St Joseph

CHU Ambroise paré

clinique Sainte Elisabeth

Notre Dame

Clinique Universitaire de Mt Godinne

CHR Luxembourg

Safety and Efficacy Study of of Docetaxel vs Docetaxel Estramustine in Hormone Refractory Prostatic Cancer

Randomized Phase Ii Trial Of Weekly Docetaxel, Estramustine And Prednisone Versus Docetaxel And Prednisone In Patient With Hormone-Resistant Prostate Cancer

prostatic neoplasms/viduriavimas

Impact of Probiotics BIFILACT® on Diarrhea in Patients Treated With Pelvic Radiation

Safety and Efficacy Study of of Docetaxel vs Docetaxel Estramustine in Hormone Refractory Prostatic Cancer

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