Rheumatoid Arthritis

Ankylosing Spondylitis

Psoriatic Arthritis

The effectiveness and use of cannabis in the management of chronic pain has been well known for many years, but has so far been illegal and therefore largely unacknowledged. We hypothesize that the use of cannabis in this population of patients with chronic joint or spinal pain is not anecdotal and responds to a need to further improve the overall management of patients. The objective of our anonymous questionnaire is to estimate the prevalence of cannabis use in patients with chronic inflammatory rheumatism.

Cannabis questionnaire

Chu Clermont Ferrand

Survey of Cannabis Use in Patients With Chronic Inflammatory Arthritis

Patients will answer the following question: Are you currently using cannabis - Yes or No

Questionnaire CAST score. It includes 6 items with answer modes coded from 0 to 4. The total score obtained by summing these 6 items can therefore vary from 0 to 24. We define users without risk for a score of less than 3, users with low risk for a score greater than or equal to 3 and less than 7, and finally those with a risk of problematic use for a score greater than or equal to 7

Spondylitis ankylosing activity was assessed by Bath Ankylosing Spondylitis Disease Activity Index (BASDAI) questionnaire.

Rheumatoid arthritis / psoriatic arthritis was assessed by Disease Activity Score including 28 joints (DAS 28). DAS 28 includes the 28 swollen joint count (28 SJC) + the 28 tender joint count (28 TJC) + patient global assessments of disease activity on a VAS, + ESR or CRP. [DAS (VS) = 0,56 x √TJC + 0,28 x √SJC + 0,7 x ln(VS) + 0,014 x VAS ; DAS (CRP) = 0,56 x √TJC + 0,28 x √SJC + 0,36 x ln(CRP + 1) + 0,014 x VAS + 0,96 ]. The scores according to EULAR criteria are: ≤2.6 for remission, >2.6 and ≤3.2 for low disease activity, >3.2 and ≤5.1 for moderate disease activity and >5.1 for high disease activity.

Functional disability was assessed by Health Assessment Questionnaire Disability Index (HAQ DI). HAQ-DI is an index that measures the impact of pathology on everyday activities such as dressing, eating, walking, etc.
The following note is allocated to each question: 0 = without any difficulty ; 1 = with some difficulty ; 2 = with great difficulty ; 3 = unable to do so

Anxiety and depression was assessed by Hospital Anxiety and Depression scale (HADs). 14 items scored from 0 to 3. Seven questions relate to anxiety (total A) and seven others to the depressive dimension (total D), allowing two scores to be obtained (maximum score of each score = 21). To detect anxious and depressive symptoms, the following interpretation can be proposed for each of the scores (A and D): - 7 or less: absence of symptoms - 8 to 10: doubtful symptoms - 11 and more: certain symptoms.

Catastrophism was assessed by Pain catastrophisme scale (PCS). PCS is a thirteen-item scale to identify and quantify the extent of catastrophism in a painful patient. Three subgroups group together the criteria related to rumination (items 8,9,10,11), exaggeration (items 6,7,13) and vulnerability (items 1,2,3,4,5,12) . Patients are asked to rate their personal experience using a five-point rating from 0 to 4. The final score can therefore vary from 0 to 52. A PCS score of 30 or more represents a relevant clinical level of catastrophism.

level of social vulnerability was assessed by Assessment of Precariousness and Health Inequalities in Health Examination Centers (EPICES) questionnaire.
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University Hospital, Clermont-Ferrand

See bellow (section "Interventions") the full description for
Measurement of aerobic exercise on cycloergometer
Measurement of muscle mass by two-photon absorptiometry: specific study
Measurement of Isometric Muscle Strength
Blood sampling for measurement of cytokine levels in the blood
Measurement of sedentarity
Psychological impact
Fatigue mesurement
Needle muscle of the vastus lateralis (This act will be limited to patients in care at Strasbourg University Hospital n=30)

See bellow (section "Interventions") the full description for
Measurement of aerobic exercise on cycloergometer
Measurement of muscle mass by two-photon absorptiometry: specific study
Measurement of Isometric Muscle Strength
Blood sampling for measurement of cytokine levels in the blood
Measurement of sedentarity
Psychological impact
Fatigue measurement
Needle muscle of the vastus lateralis (This act will be limited to patients in care at Strasbourg University Hospital n=30)

Spondylarthritis

Fatigue

Exercise Capacity

The incremental effects tests will be performed in a service specialized in the exploration of the exercise (physiology or cardiology according to the centers) in a spacious and air-conditioned room, in the presence of a medical specialist. exercise and close to the resuscitation equipment.
Before the test, weight and height will be collected. Information on the conduct of the test will be given to the patient. A multi-derivation ECG recording will be detected throughout the duration of the test and followed by a physician experienced in the ECG effort.
O2 saturation by oximetry of hens will be recorded continuously. Blood pressure will be recorded at each level. The collection of expired gases in the face mask whose tightness will be verified to measure the fractions inspired and expired in O2 and CO2 (Sensor Medics Vmax229, Yorba Linda, CA, USA) and calculations VO2 max and VCO2.
Maximal power (W max) will be recorded Patients will be encouraged during the test.

Measurement of aerobic exercise on cycloergometer

Fatigue and Skeletal Muscle Impact in Severe Axial Spondylarthritis

Maximum oxygen consumption capacity on cycloergometer during an incremental effort until exhaustion (VO2 max)

rheumatic fever/fatigue

Survey of Cannabis Use in Patients With Chronic Inflammatory Arthritis

Fatigue and Skeletal Muscle Impact in Severe Axial Spondylarthritis

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