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The Effect of Rutin on Experimental Traumatic Brain Injury and Edema in Rats

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Background/aim: The aim of the study was to evaluate the effect of rutin, which is a vitamin P1 flavonoid with anti-inflammatory and anti-edema effects, on traumatic brain injury (TBI) and edema in rats.

Studies in experimental frostbite. VI. Effect of rutin and benadryl with some notes on plaster casts and the role of edema.
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Elucidating the role of oxidative stress in the therapeutic effect of rutin on experimental acute pancreatitis.
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BACKGROUND Acute pancreatitis (AP) may be severe and cause hospitalization or death, and the available treatment is insufficient to control pancreatic inflammation and pain. Rutin is a natural flavonoid with the potential to treat AP via anti-inflammatory, antinociceptive, and antioxidant

[Protective effect of rutin against lipopolysaccharide-induced acute lung injury in mice].
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OBJECTIVE To investigate the protective effect of rutin against acute lung injury induced by lipopolysaccharide (LPS). METHODS Thirty C57BL/6 mice were randomly divided into control group, LPS-induced acute lung injury model group and treatment (LPS+Rutin) group. The pathological changes of the lung

Management of venous edema: insights from an international task force.
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An International Task Force made up of a panel of 16 experts has reviewed and objectively evaluated all aspects of chronic venous disease of the leg (CVDL). All available publications on CVDL from 1983 to 1997 were identified through computerized search in Medline and by a manual search. Next, three

Natural antioxidants enhance and prolong the oxyradical/no-related suppression by dexamethasone of ischemic and histamine paw edema in mice.
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Dexamethasone (0.1 mg/kg, s.c.) suppressed 2, 22, 12, 6, and 4% of ischemic paw edema of mice at 1, 3, 6, 18, and 40 h. Various antioxidants when given with 0.1 mg/kg Dex enhanced and prolonged the suppression. For example, 30 mg/kg of tannic acid induced suppression of 6, 52, 59, 42 and 27%,

Rutin and meloxicam attenuate paw inflammation in mice: Affecting sorbitol dehydrogenase activity.
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Rutin, naturally occurring flavonoid, has reported to cover interesting multiple pharmacological properties. This study evaluated rutin or/and meloxicam effects in paw inflammation induced by formalin in mice. Mice were divided into four groups: I-Formalin group, II-Rutin 60 mg/kg (p.o.),

[Effect of rutin and esculamine on models of aseptic inflammation].
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It was shown in experiments on rats that intraabdominal administration of silver nitrate solution induces peritonitis and the subplantar administration of histamine, serotonin and prostaglandin E2 leads to an acute paw edema. Preliminary subcutaneous administration of esculamine or rutin inhibited

Inhibitory effects of Morus nigra L. (Moraceae) against local paw edema and mechanical hypernociception induced by Bothrops jararacussu snake venom in mice.
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Bothropic venoms cause intense local damage, pain, edema, and myonecrosis. Morus nigra L. (Moraceae) has several uses in folk medicine and can be a promising candidate for the treatment of several inflammatory disorders.The present study aims to evaluate

An aqueous extract of Ilex paraguariensis reduces carrageenan-induced edema and inhibits the expression of cyclooxygenase-2 and inducible nitric oxide synthase in animal models of inflammation.
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Mate (Ilex paraguariensis) is a highly popular herbal beverage in South America due to its high content of caffeine. Its hypolipidemic and antioxidant properties are of increasing interest in the treatment of cardiovascular disorders and for weight control. In the present study, we show for the

Effect of high-pressure homogenization on formulation of TPGS loaded nanoemulsion of rutin - pharmacodynamic and antioxidant studies.
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Polyphenolic bioflavonoid, Rutin possesses wide range of pharmacological activities. However, it shows poor bioavailability when administered orally. The aim of this study was to formulate and compare the potential of nanoemulsions for the solubility enhancement of rutin (RU) by using different

Rutin has therapeutic effect on septic arthritis caused by Candida albicans.
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As of late, numerous reports have demonstrated the multiple biological activities of polyphenolic flavonoids. Amongst these reports, some indicate that the flavonoids play an important role in inflammation therapy. In this present study, we investigated the effect of rutin, a polyphenolic flavonoid,

[Effectiveness of the combination of alpha tocopherol, rutin, melilotus, and centella asiatica in the treatment of patients with chronic venous insufficiency].
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BACKGROUND The aim of this comparative clinical study was to evaluate the efficacy of the association of alphatocopherol, rutin, melilotus officinalis, and centella asiatica with oral administration in patients with chronic venous insufficiency. METHODS Thirty patients with chronic venous

Fisetin and rutin as 3C protease inhibitors of enterovirus A71.
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Enterovirus A71 (EV-A71) causes severe complications: encephalitis, pulmonary edema, and death. No effective drug has been approved for clinical use. This study investigated the antiviral effects of flavonoids against EV-A71. An in vitro inhibitor screening assay using recombinant EV-A71 3C protease

Rutin Inhibits Neuroinflammation and Provides Neuroprotection in an Experimental Rat Model of Subarachnoid Hemorrhage, Possibly Through Suppressing the RAGE-NF-κB Inflammatory Signaling Pathway.
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As is known to all, neuroinflammation plays a vital role in early brain injury pathogenesis following subarachnoid hemorrhage (SAH). It has been shown that rutin have a property of inhibiting inflammation in many kinds of animal models. However, the effect of rutin on neuroinflammation after SAH

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rutin/edema

The Effect of Rutin on Experimental Traumatic Brain Injury and Edema in Rats

Studies in experimental frostbite. VI. Effect of rutin and benadryl with some notes on plaster casts and the role of edema.

Elucidating the role of oxidative stress in the therapeutic effect of rutin on experimental acute pancreatitis.

[Protective effect of rutin against lipopolysaccharide-induced acute lung injury in mice].

Management of venous edema: insights from an international task force.

Natural antioxidants enhance and prolong the oxyradical/no-related suppression by dexamethasone of ischemic and histamine paw edema in mice.

Rutin and meloxicam attenuate paw inflammation in mice: Affecting sorbitol dehydrogenase activity.

[Effect of rutin and esculamine on models of aseptic inflammation].

Inhibitory effects of Morus nigra L. (Moraceae) against local paw edema and mechanical hypernociception induced by Bothrops jararacussu snake venom in mice.

An aqueous extract of Ilex paraguariensis reduces carrageenan-induced edema and inhibits the expression of cyclooxygenase-2 and inducible nitric oxide synthase in animal models of inflammation.

Effect of high-pressure homogenization on formulation of TPGS loaded nanoemulsion of rutin - pharmacodynamic and antioxidant studies.

Rutin has therapeutic effect on septic arthritis caused by Candida albicans.

[Effectiveness of the combination of alpha tocopherol, rutin, melilotus, and centella asiatica in the treatment of patients with chronic venous insufficiency].

Fisetin and rutin as 3C protease inhibitors of enterovirus A71.

Rutin Inhibits Neuroinflammation and Provides Neuroprotection in an Experimental Rat Model of Subarachnoid Hemorrhage, Possibly Through Suppressing the RAGE-NF-κB Inflammatory Signaling Pathway.

Išsamiausia vaistinių žolelių duomenų bazė, paremta mokslu