scoliosis/carbohydrate

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[Biochemical study of protein-carbohydrate complexes in the blood serum of patients with scoliosis].

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[Shifts of components of carbohydrate-containing proteins of the blood serum and urine in scoliosis of various etiology].

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Enhanced Recovery After Surgical Correction of Adolescent Idiopathic Scoliosis

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Background: Few publications in the literature examine enhanced recovery after scoliosis surgery (ERAS) in children, despite significant scientific interest in adults. The objective of the current study was to describe an ERAS protocol

Somatropin therapy for children with prader-willi syndrome : guidelines for use.

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Prader-Willi syndrome is a neurogenetic disorder that occurs due to the lack of a paternally expressed gene or genes on chromosome 15q11-q13. Many of the symptoms present in Prader-Willi syndrome are due to a hypothalamic-pituitary dysfunction. The main characteristics are muscular hypotonia,

Safety of growth hormone treatment in pediatric patients with idiopathic short stature.

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BACKGROUND Recombinant human GH was approved by the United States Food and Drug Administration in 2003 for the treatment of idiopathic short stature (ISS). However, to date, the safety of GH in this patient population has not been rigorously studied. OBJECTIVE The objective of this study was to

Biosynthesis of glycosaminoglycans: associated disorders and biochemical tests.

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Glycosaminoglycans (GAG) are long, unbranched heteropolymers with repeating disaccharide units that make up the carbohydrate moiety of proteoglycans. Six distinct classes of GAGs are recognized. Their synthesis follows one of three biosynthetic pathways, depending on the type of oligosaccharide

Homozygous CHST11 mutation in chondrodysplasia, brachydactyly, overriding digits, clino-symphalangism and synpolydactyly.

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BACKGROUND Carbohydrate sulfotransferase 11 (CHST11) is a membrane protein of Golgi that catalyses the transfer of sulfate to position 4 of the N-acetylgalactosamine residues of chondroitin. Chondroitin sulfate is the predominant proteoglycan in cartilage, and its sulfation is important in the

Infantile gangliosidoses: Mapping a timeline of clinical changes.

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Infantile gangliosidoses include GM1 gangliosidosis and GM2 gangliosidosis (Tay-Sachs disease, Sandhoff disease). To date, natural history studies in infantile GM2 (iGM2) have been retrospective and conducted through surveys. Compared to iGM2, there is even less natural history information available

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