The invention relates to a composition for treating or preventing prostate cancer or the recurrence thereof; including a non-aqueous extract of non-germinated broccoli seeds of the Brassica Oleracea Italica variety that are rich in sulforaphane. The extract is encapsulated by a compound selected from the group including acacia gum, maltodextrin, and the mixture thereof, and said composition can be provided in the form of a capsule, tablet, sugarcoated tablet, or film-coated tablet, and is orally administered one to three times a day at a daily dose of 2 to 200 mg.

Efstathiou; Theo

Plu; Nicolas

Sojasun Technologies

Compositions containing broccoli seeds for treatment or preventing prostate cancer

Sulforaphane has been isolated and identified as a major and very potent phase II enzyme inducer in broccoli (Brassica oleracea italica). Sulforaphane is a monofunctional inducer, inducing phase II enzymes selectively without the induction of aryl hydrocarbon receptor-dependent cytochromes P-450 (phase I enzymes). Analogues differing in the oxidation state of sulfur and the number of methylene groups were synthesized, and their inducer potencies were measured. Sulforaphane is the most potent of these analogues. Other analogues having different substituent groups in place of the methylsulfinyl group of sulforaphane were also synthesized and assessed. Of these, the most potent are 6-isothiocyanato-2-hexanone and exo-2-acetyl-6-isothiocyanatonorbornane.

The Johns Hopkins University

Chemoprotective isothiocyanates

A brassica vegetable tablet contains at least 50 .mu.g of sulforaphane and a maximum of 50 .mu.g of sulforaphane-nitrile. A process for producing a brassica vegetable product includes inactivating endogenous myrosinase enzyme in a brassica vegetable and thereafter blending the vegetable with exogenous myrosinase enzyme. The preferred process may include steam blanching as the method of inactivating the endogenous myrosinase enzyme. The preferred process may also include horseradish root as the source of exogenous myrosinase enzyme.

Amway Corporation

Brassica vegetable supplement and process for manufacture

A brassica vegetable tablet contains at least 50 ug of sulforaphane and a maximum of 50 ug of sulforaphane-nitrile. A process for producing a brassica vegetable product includes inactivating endogenous myrosinase enzyme in a brassica vegetable and thereafter blending the vegetable with exogenous myrosinase enzyme. The preferred process may include steam blanching as the method of inactivating the endogenous myrosinase enzyme. The preferred process may also include horseradish root as the source of exogenous myrosinase enzyme.

sulforaphane/bastutis

Compositions containing broccoli seeds for treatment or preventing prostate cancer

Chemoprotective isothiocyanates

Brassica vegetable supplement and process for manufacture

Brassica vegetable supplement and process for manufacture

Išsamiausia vaistinių žolelių duomenų bazė, paremta mokslu