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sulforaphane/seizures

Nuoroda įrašoma į mainų sritį
StraipsniaiKlinikiniai tyrimaiPatentai
6 rezultatus

Increased seizure susceptibility and other toxicity symptoms following acute sulforaphane treatment in mice.

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Prisijungti Registracija
Activation of Nrf2 with sulforaphane has recently gained attention as a new therapeutic approach in the treatment of many diseases, including epilepsy. As a plant-derived compound, sulforaphane is considered to be safe and well-tolerated. It is widely consumed, also by patients suffering from

Activation of Nrf2-ARE signal pathway protects the brain from damage induced by epileptic seizure.

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Prisijungti Registracija
Epilepsy remains a major medical problem for which there is no effective treatment. Oxidative damage plays an important role in epilepsy pathogenesis and may represent a target for treatment of epilepsy. Recent studies have suggested that nuclear factor erythroid 2-related factor 2 (Nrf2) binds to

Sulforaphane is anticonvulsant and improves mitochondrial function.

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Prisijungti Registracija
The nuclear factor erythroid 2-related factor 2 pathway (Nrf2) has been previously identified to protect the brain against various impacts. Here, we investigated the effect of the Nrf2 activator sulforaphane in various seizure models and hippocampal mitochondrial bioenergetics. We found that daily

The psychopharmacology of autism spectrum disorder and Rett syndrome.

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Prisijungti Registracija
Autism spectrum disorder (ASD) appears in early childhood and is characterized by persistent deficits in communication and social interaction, as well as restricted interests, repetitive behaviors, and unusual sensory issues. ASD can be idiopathic or syndromic, in the latter case representing one of

Targeting oxidative stress improves disease outcomes in a rat model of acquired epilepsy.

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Prisijungti Registracija
Epilepsy therapy is based on antiseizure drugs that treat the symptom, seizures, rather than the disease and are ineffective in up to 30% of patients. There are no treatments for modifying the disease-preventing seizure onset, reducing severity or improving prognosis. Among the potential molecular

Targeting oxidative stress improves disease outcomes in a rat model of acquired epilepsy.

Straipsnius versti gali tik registruoti vartotojai
Prisijungti Registracija
Epilepsy therapy is based on antiseizure drugs that treat the symptom, seizures, rather than the disease and are ineffective in up to 30% of patients. There are no treatments for modifying the disease-preventing seizure onset, reducing severity or improving prognosis. Among the potential molecular
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