Arthritis

Determine of percentage of each type of arthritis in children, it's prognosis and outcome of treatment in comparison with international guidelines

Observation

Arthritis in Assiut University Children Hospital

Using full history, a clinical examination and investigations can diagnose different types of arthritis attending assiut university children hospital and define prevalence of different types of arthritis

Mohamed Masoud Adb-Elmonem

Principal Investigator of pediatrics

Assiut University

Basal Proteinuria in Pregnancy

Zekai Tahir Burak Maternity Hospital

Association Between Basal Proteinuria Levels and Pregnancy Outcomes in Familial Mediterranean Fever

cantekin iskender

Perinatology

Zekai Tahir Burak Women's Health Research and Education Hospital

20 patients age of 20-60 with Rheumatoid Arthritis according to ARA 1987 revised criteria and disease activity Disease Activity Score (DAS) 3-5

Healthy controls age of 20-60 according to conclusion of preventive medicine department

Rheumatoid Arthritis

Rheumatology unit

Anterior Shoulder US - a New Access

US Investigation of Gleno-humeral Joint by Anterior Access With Measurement of Rotator Interval in Patients With Rheumatoid Arthritis and Healthy Controls

A - Measurement of GHJ thickness at 3 points and average value calculation on body supine position and with arm supinated, maximal externally rotated with elbow angle 90 degrees
By longitudinal access with transducer position laterally to coracoids along to the GHJ line, located as diagonal form lower to forward and lateral direction with demonstration the joint cartilage posteriorly and subscapular tendon anteriorly (Fig.4)
By transversal access with 90 degrees to longitudinal and at 3 points: upper with coracoids visualization, middle and lower (Fig.5-7).
B - Measurement of rotator interval with with assessment of width and higher.

Rambam Health Care Campus

•Patients randomized to placebo will receive syringes identical to active drug (100 mg prefilled syringes for subcutaneous injection) filled with drug vehicle

Patients randomized to active drug will receive Kineret (Anakinra), 100 mg prefilled syringes for subcutaneous injection, once a day for 4 months. The syringes will arrive relabeled from the supplier (SOBI) to Sheba Medical Center. They will be stored at the PI's store room in a temperature controlled refrigerator.

Familial Mediterranean Fever

Patients randomized to active drug will receive Kineret(Anakinra), 100 mg prefilled syringes for subcutaneous injection, once a day for 4 months. The syringes will arrive relabeled from the supplier (SOBI) to Sheba Medical Center. They will be stored at the PI's store room in a temperature controlled refrigerator.

Kineret

Sheba Medical Center

Kineret (Anakinra), in Adult Patients With Colchicine-Resistant Familial Mediterranean Fever

A Randomized Placebo-Controlled Study of the Efficacy and Safety of Kineret (Anakinra), in Adult Patients With Colchicine-Resistant Familial Mediterranean Fever

Total number of FMF attacks in abdominal, thoracic, skin or joint locations during the observational period (4 months) as recorded in the patient diary, devided by 4 for each patient will result in number of attacks per one month. The number of patients with less than 1 attack per month will be compared between the 2 study groups

Secondary endpoint is defined as total number of serious adverse events per 4 months in each study group. SAE is defined as an adverse event that meets one or more of the following criteria/outcomes:
Death
Life-threatening (i.e., at immediate risk of death)
In-patient hospitalization or prolongation of existing hospitalization
Persistent or significant disability/incapacity
Congenital anomaly/birth defect

synovitis/karščiavimas

Arthritis in Assiut University Children Hospital

Association Between Basal Proteinuria Levels and Pregnancy Outcomes in Familial Mediterranean Fever

Anterior Shoulder US - a New Access

Kineret (Anakinra), in Adult Patients With Colchicine-Resistant Familial Mediterranean Fever

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