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7 rezultatus
Acute synovitis and intra-articular methylprednisolone acetate in ponies.
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OBJECTIVE
To determine how acute synovitis, with and without intra-articular methylprednisolone acetate (MPA), affect synthesis of proteoglycan, total protein, and collagen in articular cartilage and total protein synthesis in synovial membrane.
METHODS
Synovitis was induced in 10 ponies by the
Effect of antigen-induced synovitis on the extensor tendons within the retinacular compartment of the dog.
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Antigen-induced proliferative synovitis was produced within the extensor retinacular compartment of one forepaw of young littermate dogs. The extensor tendons within the synovitis compartment were compared with the tendons in control compartments of the opposite forepaw. At 7 days following
Induction of osteoarthrosis in the rabbit knee joint: biochemical studies on the articular cartilage.
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Measurements of uptake in vivo of 3H-proline into 3H-hydroxyproline demonstrate that cartilage surfaces in rabbit knees with surgically induced osteoarthrosis (up to 3 months after operation) incorporated 2 to 5 times more activity into collagen than cartilage of control knees. The high uptake
Differential adherence of osteoarthritis and rheumatoid arthritis synovial fibroblasts to cartilage and bone matrix proteins and its implication for osteoarthritis pathogenesis.
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In osteoarthritis (OA), cartilage and bone fragments have been described within the synovial tissue which are surrounded by synovial cells (i.e. detritus synovitis). These cells appear to attach actively to the cartilage and bone fragments. In rheumatoid arthritis (RA), on the other hand, synovial
Characterization of Thai Mycoplasma synoviae Isolates by Sequence Analysis of Partial vlhA Gene.
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Mycoplasma synoviae (MS), a remarkable pathogen in poultry, causes subclinical infection of the upper respiratory tract and an infectious synovitis, especially in the tendon sheaths and synovial membranes of joints. Because the specific detection of MS 16S rRNA gene-based PCR was unsuitable for
Beta irradiation decreases collagen type II synthesis and increases nitric oxide production and cell death in articular chondrocytes.
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BACKGROUND
When synovitis is proved, intra-articularly injected beta emitting radionuclides like yttrium-90 ((90)Y) are used to treat the inflamed synovium.
OBJECTIVE
To study the viability, matrix production, and NO production during or after (90)Y treatment of chondrocytes.
METHODS
Monolayer,
Increased neutrophil infiltration, IL-1 production and a SAPHO syndrome-like phenotype in PSTPIP2-deficient mice.
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OBJECTIVE
Proline-serine-threonine-phosphatase-interacting protein 2 (PSTPIP2) is involved in macrophage activation, neutrophil motility and osteoclast differentiation. However, the role of PSTPIP2 in inflammation and autoinflammatory diseases is still not clear. In this study, we generated PSTPIP2
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