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Discovery for Biomarkers and Risk Factors for Postoperative Delirium in Elderly Patients With Spine Surgery

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Method: 1. Study design: This study is a prospective investigation that identifies risk factors for postoperative delirium and searches for predictive biomarkers of delirium. 2. Inclusion criteria / Exclusion Criteria 1. Inclusion criteria - Elderly patients over 70 - Eligible Surgeries: lumbar

Transcranial Alternating Current Stimulation Treating Post-stroke Depression

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Patients with post-stroke depression (PSD) have more dysfunction, poorer recovery outcomes, and higher morbidity and mortality in the first year after stroke onset than those patients without stroke. Some therapeutic methods have shown to be effective for PSD, including antidepressants, non-drug

Multi-site Transcranial Magnetic Stimulation Therapy of the Supplementary Motor Area in Children With Tourette Syndrome

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STUDY OBJECTIVES/HYPOTHESIS Tourette Syndrome (TS) is a neurodevelopmental condition that affects nearly 1% of children world-wide. While it can be treated with drugs and behavioral therapy, other modalities are being sought, especially, in cases that are resistant to standard treatment. One such

SONOlysis in Prevention of Brain InfaRctions During Internal Carotid Endarterectomy

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Results of the NASCET, ECST and ACAS studies showed that carotid endarterectomy (CEA) was a beneficial therapy for patients with a symptomatic internal carotid artery (ICA) stenosis >50% and asymptomatic ICA stenosis >60%, resp. Surgical risk of CEA varied between 2 and 15 % and even clinically

Venous Thrombus Investigation With Contrast Enhanced Ultrasound Imaging

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1. Study set up and Study design It will be an open, non-randomized prospective clinical pilot study to assess the value of contrast agents in venous thrombus investigations. a. Hypothesis - The relative signal intensity increase in decibel after intravenous contrast media injection as a tool to

Metformin in Amnestic Mild Cognitive Impairment

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The prevalence of Alzheimer's disease (AD) is expected to quadruple by the year 2047. There are no known curative or preventive measures for AD. Current treatment options for AD only address symptoms, and no treatments are available that focus on delaying the actual disease process. One of the

Neurological Outcome With Carotid Artery Stenting

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We hypothesize that the incidence of subtle neuropsychometric injury will be significantly greater than the incidence of stroke comparable to what we found in patients having carotid endarterectomy. Patients will be evaluated prospectively to determine the incidence of neurological morbidity based

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