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Cancer stem cells and uses thereof

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CROSS-REFERENCE TO RELATED APPLICATIONS This application makes reference to the following provisional U.S. patent application Ser. No. 60/739,337 entitled "Cancer Stem Cells and Uses Thereof", filed Nov. 23, 2005. The entire disclosure and contents of the above application is hereby incorporated by

Modulation of breast cancer growth by modulation of XBP1 activity

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BACKGROUND OF THE INVENTION During tumor development and progression, cancer cells encounter cytotoxic conditions such as hypoxia, nutrient deprivation, and low pH due to inadequate vascularization (Hanahan, D., et al. 2011. Cell 144, 646-674). To maintain survival and growth in the face of these

MicroRNA-based methods and assays for osteosarcoma

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BACKGROUND OF THE INVENTION There is growing evidence that tumors contain a subset of cells with stem cell-like properties. These cells, often referred to either as "cancer stem cells" (CSCs) or as "tumor-initiating cells" (TICs), are responsible for forming the bulk of tumor. These CSCs possess

Risk stratification method for a patient having a polymorphism

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BACKGROUND OF THE INVENTION Field of the Invention The invention is directed to a risk stratification method for a patient in a disease state and particularly to a patient having a polymorphism and a tumor, such as a hemangioma. Background Infantile hemangioma (IH) is the most common tumor of the

Cyclic adhesion inhibitors

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SUMMARY OF THE INVENTION The invention relates to novel cyclopeptides of the formula I in which D and E in each case independently of one another are Gly, Ala, .beta.-Ala, Asn, Asp, Asp(OR), Arg, Cha, Cys, Gln, Glu, His, Ile, Leu, Lys, Lys(Ac), Lys(AcNH.sub.2), Lys(AcSH), Met, Nal, Nle, Orn, Phe,

Human G-protein coupled receptor

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The present invention relates to novel identified polynucleotides, polypeptides encoded by them and to the use of such polynucleotides and polypeptides, and to their production. More particularly, the polynucleotides and polypeptides of the present invention relate to a G-protein coupled receptor

Antibodies immunospecific for a novel human G-protein coupled receptor family

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The present invention relates to novel identified polynucleotides, polypeptides encoded by them and to the use of such polynucleotides and polypeptides, and to their production. More particularly, the polynucleotides and polypeptides of the present invention relate to a G-protein coupled receptor

Medical image processing apparatus and ultrasonic imaging apparatus

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BACKGROUND OF THE INVENTION 1. Field of the Invention The present invention relates to a medical image processing apparatus that makes a determination regarding the presence of a tumor based on ultrasonic images acquired by capturing a subject to which a contrast agent has been administered. The
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